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CT Brain Perfusion in the Prediction of Final Infarct Volume: A Prospective Study of Different Software Settings for Acute Ischemic Core Calculation

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081740%3A_____%2F22%3A00562261" target="_blank" >RIV/68081740:_____/22:00562261 - isvavai.cz</a>

  • Alternative codes found

    RIV/00064173:_____/22:43924022 RIV/00216208:11120/22:43924022 RIV/00216208:11130/22:10448508

  • Result on the web

    <a href="https://www.mdpi.com/2075-4418/12/10/2290" target="_blank" >https://www.mdpi.com/2075-4418/12/10/2290</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.3390/diagnostics12102290" target="_blank" >10.3390/diagnostics12102290</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    CT Brain Perfusion in the Prediction of Final Infarct Volume: A Prospective Study of Different Software Settings for Acute Ischemic Core Calculation

  • Original language description

    CT perfusion (CTP) is used for the evaluation of brain tissue viability in patients with acute ischemic stroke (AIS). We studied the accuracy of three different syngo.via software (SW) settings for acute ischemic core estimation in predicting the final infarct volume (FIV). The ischemic core was defined as follows: Setting A: an area with cerebral blood flow (CBF) < 30% compared to the contralateral healthy hemisphere. Setting B: CBF < 20% compared to contralateral hemisphere. Setting C: area of cerebral blood volume (CBV) < 1.2 mL/100 mL. We studied 47 AIS patients (aged 68 ± 11.2 years) with large vessel occlusion in the anterior circulation, treated in the early time window (up to 6 h), who underwent technically successful endovascular thrombectomy (EVT). FIV was measured on MRI performed 24 ± 2 h after EVT. In general, all three settings correlated with each other, however, the absolute agreement between acute ischemic core volume on CTP and FIV on MRI was poor, intraclass correlation for all three settings was between 0.64 and 0.69, root mean square error of the individual observations was between 58.9 and 66.0. Our results suggest that using CTP syngo.via SW for prediction of FIV in AIS patients in the early time window is not appropriate.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    50101 - Psychology (including human - machine relations)

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2022

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Diagnostics

  • ISSN

    2075-4418

  • e-ISSN

    2075-4418

  • Volume of the periodical

    12

  • Issue of the periodical within the volume

    10

  • Country of publishing house

    CH - SWITZERLAND

  • Number of pages

    10

  • Pages from-to

    2290

  • UT code for WoS article

    000872352500001

  • EID of the result in the Scopus database

    2-s2.0-85140627573