Hemoglobin adducts in 1,3-butadiene exposed Czech workers: Female?male comparisons

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F10%3A00347670" target="_blank" >RIV/68378041:_____/10:00347670 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Hemoglobin adducts in 1,3-butadiene exposed Czech workers: Female?male comparisons

Original language description

The results of this study confirm the findings of the previous molecular epidemiological study of female and male 1,3-butadiene (BD) exposed Czech workers, showing that females appeared to absorb or metabolize less BD per unit exposure conc. that did males (based on metabolite conc. in urine). In this study, another biomarker to measure a second metabolite of BD was used. The authors measured production and accumulation of the 1,2-dihydroxy-3,4-epoxybutane (EBD) metabolite as reflected in THB-Val hemoglobin adduct concentrations. In both the control and exposed groups mean THB-Val concentrations were significantly higher for males than females. It was also found that the size of difference increased with exposure.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

DN - Environmental impact on health

OECD FORD branch

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Project

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Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Chemico-Biological Interactions

ISSN

0009-2797

e-ISSN

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Volume of the periodical

188

Issue of the periodical within the volume

3

Country of publishing house

IE - IRELAND

Number of pages

9

Pages from-to

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UT code for WoS article

000285169100035

EID of the result in the Scopus database

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