Noise exposure during early development influences the acoustic startle reflex in adult rats

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F11%3A00363983" target="_blank" >RIV/68378041:_____/11:00363983 - isvavai.cz</a>
Alternative codes found
RIV/71226401:_____/11:#0000092
Result on the web
<a href="http://dx.doi.org/10.1016/j.physbeh.2010.12.010" target="_blank" >http://dx.doi.org/10.1016/j.physbeh.2010.12.010</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.physbeh.2010.12.010" target="_blank" >10.1016/j.physbeh.2010.12.010</a>

Result language
angličtina
Original language name
Noise exposure during early development influences the acoustic startle reflex in adult rats
Original language description
In the present study, the behavioral consequences of brief noise exposure during the critical period in rats were assessed in adult rats using the acoustic startle reflex and prepulse inhibition of the acoustic startle reflex. The results showed that although the hearing hresholds in exposed and control animals were not different, a reduced strength of the startle reflex and markedly different efficacy of prepulse inhibition were observed between both groups of animals. Our findings demonstrate that brief noise exposure in rat pups results in altered behavioral responses to sounds in adulthood, indicating, accompanied by anomalies in intensity coding and loudness perception.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
—

Project
<a href="/en/project/GA309%2F07%2F1336" target="_blank" >GA309/07/1336: Acoustical signal processing in the neuronal circuits of the auditory system</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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