Age-related changes in the acoustic startle reflex in Fischer 344 and Long Evans rats

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F12%3A00383080" target="_blank" >RIV/68378041:_____/12:00383080 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.exger.2012.09.001" target="_blank" >http://dx.doi.org/10.1016/j.exger.2012.09.001</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.exger.2012.09.001" target="_blank" >10.1016/j.exger.2012.09.001</a>

Result language
angličtina
Original language name
Age-related changes in the acoustic startle reflex in Fischer 344 and Long Evans rats
Original language description
Hearing thresholds, the strength of the acoustic startle responses and the efficiency of the prepulse inhibition were assessed in young, middle-aged, and aged Long Evans and Fischer 344 rats. Fischer 344 rats showed larger age-related hearing threshold shifts and lower amplitudes of startle responses at an earlier age than in Long Evans rats. A reduction of the prepulse inhibition was observed in aged rats of both strains. The results indicate that the acoustic startle response may serve as an indicatorof central presbycusis.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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