Tailor-Made Fluorescent Trilobolide To Study Its Biological Relevance

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F14%3A00436080" target="_blank" >RIV/68378041:_____/14:00436080 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11140/14:10279690 RIV/60461373:22330/14:43897193
Result on the web
<a href="http://dx.doi.org/10.1021/jm500690j" target="_blank" >http://dx.doi.org/10.1021/jm500690j</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/jm500690j" target="_blank" >10.1021/jm500690j</a>

Result language
angličtina
Original language name
Tailor-Made Fluorescent Trilobolide To Study Its Biological Relevance
Original language description
Anotace v a.j.: Trilobolide (Tb) is a potent natural counterpart of thapsigargin. The live-cell imaging of the prepared bioconjugates brought clear evidence that Tb?Bodipy localized in the endoplasmic reticulum (ER) of various cancer cell lines. Cytotoxicity of Tb conjugates and impact on the mitochondrial physiology and nitric oxide release and cytokine secretion were also studied.
Czech name
—
Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FR - Pharmacology and apothecary chemistry
OECD FORD branch
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Project
<a href="/en/project/GA14-04329S" target="_blank" >GA14-04329S: Relationship between biological activities of sesquiterpene lactones to their subcellular localization</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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