Chromosomal damage as markers of genotoxic effect and carcinogenesis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F15%3A00475586" target="_blank" >RIV/68378041:_____/15:00475586 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Chromosomal damage as markers of genotoxic effect and carcinogenesis
Original language description
Many cancers often arise from cells unable to maintain genomic and chromosomal instability. Recurrent chromosomal aberrations (CAs) arise through a clonal growth of cells with specific translocations, deletions or amplifications of chromosomal regions or whole chromosomes and many specific CAs are causative events in malignant transformation. In our studies we compared frequencies of CAs in patients with incident lung, breast and colorectal cancer. Additionally, we have also searched for genetic background that modulates chromosomal instability in humans. The DNA repair characteristics have been discussed as well.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů