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Composite Hydrogel Scaffolds for the Regeneration of Osteochondral Defects

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F16%3A00476178" target="_blank" >RIV/68378041:_____/16:00476178 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Composite Hydrogel Scaffolds for the Regeneration of Osteochondral Defects

  • Original language description

    Even in 1982, Benya and Shaffer reported re-expression of chondrogenic phenotype of dedifferentiated chondrocytes after their embedding intro three-dimensional agarose hydrogel. From that time many different hydrogel scaffolds were studied in vitro and in vivo. Hydrogels provide a proper environment for cell growth and differentiation . However, they have several limitations, e.g. low mechanical properties or fast degradation, which leads to development of synthetic hydrogels and/or composite scaffolds. Composite scaffolds can be prepared as blend hydrogels, but often hydrogel form a separate chondral part of multi-layered scaffolds.

  • Czech name

  • Czech description

Classification

  • Type

    C - Chapter in a specialist book

  • CEP classification

  • OECD FORD branch

    30402 - Technologies involving the manipulation of cells, tissues, organs or the whole organism (assisted reproduction)

Result continuities

  • Project

    <a href="/en/project/LO1309" target="_blank" >LO1309: Cell Therapy and Tissue Repair</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2016

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Book/collection name

    Novel Biomaterials in Regenerative Medicine

  • ISBN

    978-80-88113-69-0

  • Number of pages of the result

    11

  • Pages from-to

    188-198

  • Number of pages of the book

    276

  • Publisher name

    Epika

  • Place of publication

    2016

  • UT code for WoS chapter