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The Effects of Sterilization Techniques on Cell Biocompatibility Using Needleless Electrospun PCL Nanofibers

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F18%3A00500083" target="_blank" >RIV/68378041:_____/18:00500083 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    The Effects of Sterilization Techniques on Cell Biocompatibility Using Needleless Electrospun PCL Nanofibers

  • Original language description

    Recently, the needleless electrospinning technique has attracted growing attention within tissue engineering applications. Polycaprolactone nanofibers sterilized using ethylene oxide (EtOx) and ethanol (EtOH), were tested as a universal scaffold suitable for the culture of skin cells (fibroblasts and keratinocytes). There were no morphological or chemical changes in the PCL scaffolds detected, together with no difference in cell adhesion and proliferation. However, a higher metabolic activity of the cells was observed on the EtOH-sterilized scaffolds versus the EtOX-sterilized samples in vitro.

  • Czech name

  • Czech description

Classification

  • Type

    C - Chapter in a specialist book

  • CEP classification

  • OECD FORD branch

    10601 - Cell biology

Result continuities

  • Project

    <a href="/en/project/LO1508" target="_blank" >LO1508: Genomics and proteomics in the study of mechanisms of biological effects of produced nanoparticles</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2018

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Book/collection name

    Nanostructures in Biomedicine: Their Regenerative and toxic properties

  • ISBN

    978-80-906655-7-6

  • Number of pages of the result

    6

  • Pages from-to

    123-128

  • Number of pages of the book

    198

  • Publisher name

    Proxima Tisk, s.r.o.

  • Place of publication

    Praha 3

  • UT code for WoS chapter