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Skin Tissue Engineering and bFGF for Fibroblast Stimulation

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F18%3A00500140" target="_blank" >RIV/68378041:_____/18:00500140 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Skin Tissue Engineering and bFGF for Fibroblast Stimulation

  • Original language description

    Skin is the largest organ of the body and serves as a barrier between the internal and external environment. Its integrity is crucial for thermoregulation, hydration retention and especially protection against infection. In order to facilitate its essential functions, the skin continuously undergoes renewal. Wound healing is a complex process which involves the coordinated action of many bioactive molecules and numerous cell types. Even though the regeneration capacity of the organism itself is wide, there are certain conditions which can prolong the healing or even make it impossible thus leading to a chronic wound, these can also increase health care costs. Tissue engineering brings new alternative strategies of wound healing and tissue regeneration. A noncellular scaffold made of biocompatible material enriched with a stimulating growth factor, could support and accelerate damaged tissue restoration. This would be beneficial for patients with critical size skin defects such as diabetic ulcers or with deep burns. This chapter reviews the basic principles of skin tissue engineering. It will be focused on skin anatomy, skin substitutes and the basic fibroblast growth factor function.

  • Czech name

  • Czech description

Classification

  • Type

    C - Chapter in a specialist book

  • CEP classification

  • OECD FORD branch

    10601 - Cell biology

Result continuities

  • Project

    <a href="/en/project/LO1508" target="_blank" >LO1508: Genomics and proteomics in the study of mechanisms of biological effects of produced nanoparticles</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2018

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Book/collection name

    Nanostructures in Biomedicine: Their Regenerative and toxic properties

  • ISBN

    978-80-906655-7-6

  • Number of pages of the result

    4

  • Pages from-to

    161-164

  • Number of pages of the book

    198

  • Publisher name

    Proxima Tisk, s.r.o.

  • Place of publication

    Praha 3

  • UT code for WoS chapter