Skin Tissue Engineering and bFGF for Fibroblast Stimulation
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F18%3A00500140" target="_blank" >RIV/68378041:_____/18:00500140 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Skin Tissue Engineering and bFGF for Fibroblast Stimulation
Original language description
Skin is the largest organ of the body and serves as a barrier between the internal and external environment. Its integrity is crucial for thermoregulation, hydration retention and especially protection against infection. In order to facilitate its essential functions, the skin continuously undergoes renewal. Wound healing is a complex process which involves the coordinated action of many bioactive molecules and numerous cell types. Even though the regeneration capacity of the organism itself is wide, there are certain conditions which can prolong the healing or even make it impossible thus leading to a chronic wound, these can also increase health care costs. Tissue engineering brings new alternative strategies of wound healing and tissue regeneration. A noncellular scaffold made of biocompatible material enriched with a stimulating growth factor, could support and accelerate damaged tissue restoration. This would be beneficial for patients with critical size skin defects such as diabetic ulcers or with deep burns. This chapter reviews the basic principles of skin tissue engineering. It will be focused on skin anatomy, skin substitutes and the basic fibroblast growth factor function.
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
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OECD FORD branch
10601 - Cell biology
Result continuities
Project
<a href="/en/project/LO1508" target="_blank" >LO1508: Genomics and proteomics in the study of mechanisms of biological effects of produced nanoparticles</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Nanostructures in Biomedicine: Their Regenerative and toxic properties
ISBN
978-80-906655-7-6
Number of pages of the result
4
Pages from-to
161-164
Number of pages of the book
198
Publisher name
Proxima Tisk, s.r.o.
Place of publication
Praha 3
UT code for WoS chapter
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