Circulating biomarkers for early detection and clinical management of colorectal cancer
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F19%3A00517914" target="_blank" >RIV/68378041:_____/19:00517914 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/19:10396557
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S0098299719300093?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0098299719300093?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.mam.2019.06.002" target="_blank" >10.1016/j.mam.2019.06.002</a>
Alternative languages
Result language
angličtina
Original language name
Circulating biomarkers for early detection and clinical management of colorectal cancer
Original language description
New non-invasive approaches that can complement and improve on current strategies for colorectal cancer (CRC) screening and management are urgently needed. A growing number of publications have documented that components of tumors, which are shed into the circulation, can be detected in the form of liquid biopsies and can be used to detect CRC at early stages, to predict response to certain therapies and to detect CRC recurrence in a minimally invasive way. The analysis of circulating tumor DNA (ctDNA), tumor-derived cells (CTC, circulating tumor cells) or circulating microRNA (miRNA) in blood and other body fluids, have a great potential to improve different aspects of CRC management. The challenge now is to find which types of components, biofluids and detection methods would be the most suitable to be applied in the different steps of CRC detection and treatment. This chapter will provide an up to date review on ctDNA, CTCs and circulating miRNAs as new biomarkers for CRC, either for clinical management or early detection, highlighting their advantages and limitations.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30101 - Human genetics
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Molecular Aspects of Medicine
ISSN
0098-2997
e-ISSN
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Volume of the periodical
69
Issue of the periodical within the volume
SI
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
16
Pages from-to
107-122
UT code for WoS article
000486385900010
EID of the result in the Scopus database
2-s2.0-85067210363