Biomaterials and Magnetic Stem Cell Delivery in the Treatment of Spinal Cord Injury
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F20%3A00518561" target="_blank" >RIV/68378041:_____/20:00518561 - isvavai.cz</a>
Result on the web
<a href="https://link.springer.com/article/10.1007%2Fs11064-019-02808-2" target="_blank" >https://link.springer.com/article/10.1007%2Fs11064-019-02808-2</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s11064-019-02808-2" target="_blank" >10.1007/s11064-019-02808-2</a>
Alternative languages
Result language
angličtina
Original language name
Biomaterials and Magnetic Stem Cell Delivery in the Treatment of Spinal Cord Injury
Original language description
Spinal cord injury (SCI) is a serious trauma, which often results in a permanent loss of motor and sensory functions, pain and spasticity. Despite extensive research, there is currently no available therapy that would restore the lost functions after SCI in human patients. Advanced treatments use regenerative medicine or its combination with various interdisciplinary approaches such as tissue engineering or biophysical methods. This review summarizes and critically discusses the research from specific interdisciplinary fields in SCI treatment such as the development of biomaterials as scaffolds for tissue repair, and using a magnetic field for targeted cell delivery. We compare the treatment effects of synthetic non-degradable methacrylate-based hydrogels and biodegradable biological scaffolds based on extracellular matrix. The systems using magnetic fields for magnetically guided delivery of stem cells loaded with magnetic nanoparticles into the lesion site are then suggested and discussed. © 2019, Springer Science+Business Media, LLC, part of Springer Nature.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30404 - Biomaterials (as related to medical implants, devices, sensors)
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Neurochemical Research
ISSN
0364-3190
e-ISSN
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Volume of the periodical
45
Issue of the periodical within the volume
1
Country of publishing house
US - UNITED STATES
Number of pages
9
Pages from-to
171-179
UT code for WoS article
000511696200015
EID of the result in the Scopus database
2-s2.0-85065046135