Cloning and expression of PARP-3 (Adprt3) and U3-55k, two genes closely linked on mouse chromosome 9.

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F02%3A23049036" target="_blank" >RIV/68378050:_____/02:23049036 - isvavai.cz</a>

Alternative codes found

RIV/68378050:_____/02:00102941 RIV/68378050:_____/02:00191542

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Cloning and expression of PARP-3 (Adprt3) and U3-55k, two genes closely linked on mouse chromosome 9.

Original language description

We characterized the mouse PARP-3 gene encoding poly(ADP-ribose) polymerase 3 and the closely linked U3-55k gene coding for the U3 small nucleolar ribonucleoprotein complex-associated 55-kilodalton protein. The two genes are located in a head-to-head orientation on mouse chromosome 9 and are linked by an approximately 1.5-kb putative bi-directional promoter region. This gene arrangement is conserved between mouse and human orthologues. Using a panel of mRNAs from various adult mouse tissues and organs,the expression profiles of PARP-3, U3-55k, PARP-2 and PARP-1 genes were determined. PARP-3 expression exhibited marked differences among the individual tissues and some degree of tissue specificity, ranging from the highest transcript levels in the skeletal muscle to the barely detectable expression in the whole=brain and testis mRNA. In contrast to PARP-3, the other three genes were expressed ubiquitously, with less variability of mRNA levels.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EB - Genetics and molecular biology

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2002

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Folia Biologica (Praha)

ISSN

0015-5500

e-ISSN

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Volume of the periodical

48

Issue of the periodical within the volume

5

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

10

Pages from-to

182-191

UT code for WoS article

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EID of the result in the Scopus database

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