Molecular cloning, E.coli expression and purification of SCFV antibody fragments of diagnostic/therapeutic interest.

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F03%3A23033034" target="_blank" >RIV/68378050:_____/03:23033034 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Molecular cloning, E.coli expression and purification of SCFV antibody fragments of diagnostic/therapeutic interest.
Original language description
We describe molecular cloning, expression, purification and properties of two single chain antibody variable fragments (scFv) of potential diagnostic use, namely scFv M75 and scFv Tu-20. The former scFv is derived from a monoclonal antibody M75 specificfor a cell surface protein MN/CA IX, strongly associated with many types of human carcinomas. The latter scFv is derived from a monoclonal antibody TU-20 specific for neuronal beta-III-tubulin.
Czech name
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Czech description
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Project
<a href="/en/project/GV203%2F98%2FK023" target="_blank" >GV203/98/K023: Protein crystallography analyses of liganded proteinase of human immunodeficiency virus ( HIV ) for design of novel anti - AIDS compounds</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2003
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
Material Structure in Chemistry, Biology, Physics and Technology.
ISBN
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ISSN
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e-ISSN
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Number of pages
1
Pages from-to
56
Publisher name
Czech and Slovak Crystallographic Association
Place of publication
Praha,
Event location
Nové Hrady [CZ]
Event date
Mar 13, 2003
Type of event by nationality
CST - Celostátní akce
UT code for WoS article
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