Association of CD99 short and long forms with MHC class I, MHC class II and tetraspanin CD81 and recruitment into immunological synapses
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F11%3A00370115" target="_blank" >RIV/68378050:_____/11:00370115 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1186/1756-0500-4-293" target="_blank" >http://dx.doi.org/10.1186/1756-0500-4-293</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1186/1756-0500-4-293" target="_blank" >10.1186/1756-0500-4-293</a>
Alternative languages
Result language
angličtina
Original language name
Association of CD99 short and long forms with MHC class I, MHC class II and tetraspanin CD81 and recruitment into immunological synapses
Original language description
We analyzed the association of CD99 with other cell surface molecules involved in T cell activation. We demonstrate the association of MHC class I, MHC class II and tetraspanin CD81 with CD99 molecules on the cell surface. Association of CD99 with its partners was observed for both isoforms. In addition, we determined that CD99 is a lipid raft-associated membrane protein and is recruited into the immunologic synapse during T cell activation. The implication of CD99 on T cell activation was investigated.Inhibition of anti-CD3 induced T cell proliferation by an anti-CD99 monoclonal antibody was observed.
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
—
Result continuities
Project
—
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
BMC Research Notes
ISSN
1756-0500
e-ISSN
—
Volume of the periodical
4
Issue of the periodical within the volume
—
Country of publishing house
GB - UNITED KINGDOM
Number of pages
13
Pages from-to
293
UT code for WoS article
—
EID of the result in the Scopus database
—