New insight into transcription of human endogenous retroviral elements
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F13%3A00394696" target="_blank" >RIV/68378050:_____/13:00394696 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.nbt.2012.11.009" target="_blank" >http://dx.doi.org/10.1016/j.nbt.2012.11.009</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.nbt.2012.11.009" target="_blank" >10.1016/j.nbt.2012.11.009</a>
Alternative languages
Result language
angličtina
Original language name
New insight into transcription of human endogenous retroviral elements
Original language description
It is generally assumed that human endogenous retroviral elements (HERVs) belong to the class of genomic repetitive nucleotide sequences often called junk DNA?. These elements were categorized to families, and members of some of these families (e.g. HERV-H, HERV-W and HERV-K) were shown to be transcribed. These transcriptions were associated with several severe diseases such as mental disorders, AIDS, autoimmune diseases and cancer. In this review we discuss several bioinformatics strategies for genome-wide scan of HERVs transcription using high-throughput RNA sequencing on several platforms. We show that many more HERVs than previously described are transcribed to various levels and we discuss possible implications of these transcriptions.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GCP305%2F10%2FJ052" target="_blank" >GCP305/10/J052: Functional analysis of endogenous retroviral elements in human genome: possible association with cancers</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
New Biotechnology
ISSN
1871-6784
e-ISSN
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Volume of the periodical
30
Issue of the periodical within the volume
3
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
5
Pages from-to
314-318
UT code for WoS article
000317240000010
EID of the result in the Scopus database
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