Membrane microdomains in immunoreceptor signaling
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F14%3A00435782" target="_blank" >RIV/68378050:_____/14:00435782 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.febslet.2014.05.047" target="_blank" >http://dx.doi.org/10.1016/j.febslet.2014.05.047</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.febslet.2014.05.047" target="_blank" >10.1016/j.febslet.2014.05.047</a>
Alternative languages
Result language
angličtina
Original language name
Membrane microdomains in immunoreceptor signaling
Original language description
Membrane microdomains denoted commonly as lipid rafts (or membrane rafts) have been implicated in T-cell receptor (TCR), and more generally immunoreceptor, signaling for over 25 years. However, this area of research has been complicated by doubts about the real nature (and even existence) of these membrane entities, especially because of methodological problems connected with possible detergent artefacts. Recent progress in biophysical approaches and functional studies of raft resident proteins apparently clarified many controversial aspects in this area. At present, the prevailing view is that these membrane microdomains are indeed involved in many aspects of cell biology, including immunoreceptor signaling. Moreover, several other types of raft-likemicrodomains (perhaps better termed nanodomains) have been described, which apparently also play important biological roles. (C) 2014 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GBP302%2F12%2FG101" target="_blank" >GBP302/12/G101: Molecular mechanisms of signaling through leukocyte receptors their role in health and disease.</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
FEBS Letters
ISSN
0014-5793
e-ISSN
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Volume of the periodical
588
Issue of the periodical within the volume
15
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
6
Pages from-to
2392-2397
UT code for WoS article
000339535200006
EID of the result in the Scopus database
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