Introduction to RNAi and miRNA pathways
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F19%3A00523483" target="_blank" >RIV/68378050:_____/19:00523483 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Introduction to RNAi and miRNA pathways
Original language description
RNA silencing denotes a group of pathways, which utilize small RNAs as sequence-specific guides for repressing gene expression. Two related RNA silencing pathways exist in animals and plants: RNA interference (RNAi) and microRNA (miRNA) pathway. While the miRNA pathway serves to regulate endogenous protein-coding gene expression, RNAi serves as a form of innate immunity targeting viruses and mobile elements, although it occasionally also acquired function in protein-coding gene regulation. The aim of the following text is to provide an elementary introduction into RNAi and miRNA pathways for a series of taxon-specific and feature-specific reviews, which follow. The idea is to bring up common general principles allowing the reader to better navigate through common and derived mechanisms and functions of RNA silencing presented taxon-oriented review. The whole review series has been derived from a material for an expert report for the European Food and Safety Agency, which I wished to reorganize and make more accessible to the scientific community.
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
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OECD FORD branch
10602 - Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology
Result continuities
Project
<a href="/en/project/LO1220" target="_blank" >LO1220: CZ-OPENSCREEN: National infrastructure for chemical biology</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Introduction to RNAi and miRNA pathways
ISBN
978-80-246-4372-4
Number of pages of the result
24
Pages from-to
1-339
Number of pages of the book
339
Publisher name
Karolinum
Place of publication
Praha
UT code for WoS chapter
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