RNAi and miRNA pathways in annelids and molluscs
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F19%3A00523490" target="_blank" >RIV/68378050:_____/19:00523490 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
RNAi and miRNA pathways in annelids and molluscs
Original language description
RNA silencing denotes sequence-specific repression mediated by small RNAs. In metazoa, there are two mechanistically closely related pathways: RNA interference (RNAi) and microRNA (miRNA) pathway. The miRNA pathway serves to regulate endogenous protein-coding gene expression and has been implicated in many biological processes. RNAi generally serves as a form of innate immunity targeting viruses and mobile elements. This review is summarizing information about RNAi and miRNA pathways in protostome phyla: Annelida and Mollusca. The molecular mechanism of dsRNA and miRNA pathways in annelids remain largely unexplored. The available information points towards coexistence of miRNA and RNAi pathways, however, their integration or genetic separation remain unclear. Molluscs are an interesting taxon, which appears to have a unique setup of RNA silencing possibly employing a single Argonaute protein while it also employs interferon-like pathway elements.
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
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OECD FORD branch
10602 - Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology
Result continuities
Project
<a href="/en/project/LO1220" target="_blank" >LO1220: CZ-OPENSCREEN: National infrastructure for chemical biology</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Introduction to RNAi and miRNA pathways
ISBN
978-80-246-4372-4
Number of pages of the result
14
Pages from-to
1-339
Number of pages of the book
339
Publisher name
Karolinum
Place of publication
Praha
UT code for WoS chapter
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