RNAi and miRNA pathways in birds
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F19%3A00523487" target="_blank" >RIV/68378050:_____/19:00523487 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
RNAi and miRNA pathways in birds
Original language description
RNA silencing denotes sequence-specific repression mediated by small RNAs. In vertebrates, there are two closely related pathways, which share several protein factors: RNA interference (RNAi) and microRNA (miRNA) pathway. The miRNA pathway serves to regulate endogenous protein-coding gene expression and has been implicated in many biological processes. RNAi generally serves as a form of innate immunity targeting viruses and mobile elements. This work reviews miRNA and RNAi pathways in birds. Although the available literature on RNA silencing in birds is very limited, many features can be deduced from the genomic data in the public domain. miRNA, RNAi and other dsRNA-responding pathways in birds appear very much like those in mammals, important bird-specific features of RNA silencing pathways are yet to be identified. The miRNA pathway is likely the dominant small RNA pathway while the existence and functionality of endogenous RNAi remains unclear. Some variations may be present in the main bird antiviral interferon system.
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
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OECD FORD branch
10602 - Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology
Result continuities
Project
<a href="/en/project/LO1220" target="_blank" >LO1220: CZ-OPENSCREEN: National infrastructure for chemical biology</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Introduction to RNAi and miRNA pathways
ISBN
978-80-246-4372-4
Number of pages of the result
14
Pages from-to
1-339
Number of pages of the book
339
Publisher name
Karolinum
Place of publication
Praha
UT code for WoS chapter
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