Breaking DNA strands by extreme-ultraviolet laser pulses in vacuum
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F15%3A00448547" target="_blank" >RIV/68378271:_____/15:00448547 - isvavai.cz</a>
Alternative codes found
RIV/61389005:_____/15:00448547 RIV/68407700:21340/15:00235107
Result on the web
<a href="http://dx.doi.org/10.1103/PhysRevE.91.042718" target="_blank" >http://dx.doi.org/10.1103/PhysRevE.91.042718</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1103/PhysRevE.91.042718" target="_blank" >10.1103/PhysRevE.91.042718</a>
Alternative languages
Result language
angličtina
Original language name
Breaking DNA strands by extreme-ultraviolet laser pulses in vacuum
Original language description
Ionizing radiation induces a variety of DNA damages including single-strand breaks (SSBs), double-strand breaks (DSBs), abasic sites, modified sugars, and bases. We have studied the nature of DNA damage induced directly by the pulsed 46.9nm (26.5 eV) radiation provided by an extreme ultraviolet (XUV) capillary-discharge Ne-like Ar laser (CDL). Doses up to 45 kGy were delivered with a repetition rate of 3 Hz. We studied the dependence of the yield of SSBs and DSBs of a simple model of DNA molecule (pBR322) on the CDL pulse fluence. Agarose gel electrophoresis method was used for determination of both SSB and DSB yields. The action cross sections of the single and double-strand breaks of pBR322 plasmid DNA in solid state were determined. We observed an increase in the efficiency of strand-break induction in the supercoiled DNA as a function of laser pulse fluence. Results are compared to those acquired at synchrotron radiation facilities and other sources of XUV and soft x-ray radiation.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
BO - Biophysics
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Physical Review. E
ISSN
1539-3755
e-ISSN
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Volume of the periodical
91
Issue of the periodical within the volume
4
Country of publishing house
US - UNITED STATES
Number of pages
8
Pages from-to
"042718-1"-"042718-8"
UT code for WoS article
000353637500008
EID of the result in the Scopus database
2-s2.0-84929192771