Magnetron-sputtered niobium nanoparticles for molecular imaging of brain tissues through surface-assisted laser desorption/ionization mass spectrometry
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F22%3A00564922" target="_blank" >RIV/68378271:_____/22:00564922 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11320/22:10451744 RIV/00216224:14310/22:00129244
Result on the web
<a href="https://doi.org/10.1021/acsanm.2c02734" target="_blank" >https://doi.org/10.1021/acsanm.2c02734</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/acsanm.2c02734" target="_blank" >10.1021/acsanm.2c02734</a>
Alternative languages
Result language
angličtina
Original language name
Magnetron-sputtered niobium nanoparticles for molecular imaging of brain tissues through surface-assisted laser desorption/ionization mass spectrometry
Original language description
The Nb NPs are synthesized by a magnetron sputtering inert gas aggregation technique, which avoids the use of wet chemical pathways and allows the direct deposition of the NPs onto biological specimens. The NPs are partially oxidized and consist of a body-centered cubic (bcc) polycrystalline metal Nb core enclosed by an amorphous Nb2O5 shell. When seeded onto slices of the mouse brain, the Nb NPs form an effective matrix for high-resolution SALDI MSI of complex biological samples in both negative and positive ionization modes. The use of ultrahigh-resolution mass spectrometry allowed the identification of different Nb adducts and multiple phospholipid ion classes at m/z < 1000 This work qualifies Nb NPs as an efficient, accessible, and easy-to-handle matrix for SALDI MSI for the first time. In addition, it highlights the potential utilization of other, yet unexplored transition-metal NPs, motivating their future research.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
21002 - Nano-processes (applications on nano-scale); (biomaterials to be 2.9)
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
ACS Applied Nano Materials
ISSN
2574-0970
e-ISSN
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Volume of the periodical
5
Issue of the periodical within the volume
9
Country of publishing house
US - UNITED STATES
Number of pages
11
Pages from-to
12865-12875
UT code for WoS article
000859044000001
EID of the result in the Scopus database
2-s2.0-85138770225