Resolving measurement of large (~ GDa) chemical/biomolecule complexes with multimode nanomechanical resonators
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F22%3A00567870" target="_blank" >RIV/68378271:_____/22:00567870 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1016/j.snb.2021.131062" target="_blank" >https://doi.org/10.1016/j.snb.2021.131062</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.snb.2021.131062" target="_blank" >10.1016/j.snb.2021.131062</a>
Alternative languages
Result language
angličtina
Original language name
Resolving measurement of large (~ GDa) chemical/biomolecule complexes with multimode nanomechanical resonators
Original language description
Mass sensing by nanomechanical resonators can be routinely performed for analytes of mass ranging from kDa to tens of MDa. Measurement of the heavier analytes (up to hundreds of GDa) that are relevant to viruses, and many biological and chemical complexes, still remains one of the main challenges to be solved. Some studies propose the heavy analyte identification by accounting for its mass, stiffness and binding effects. However, the necessity of using the sophisticated computational tools complicates their widespread use in the nanomechanical mass spectrometry. Here, we report on the heavy analyte mass spectrometry (~ GDa) using the multimode nanomechanical resonators, which is directly applicable to analytes of arbitrary mass, stiffness and dimensions. This identification, based on the simultaneous measurement of the multiple by analyte induced resonant frequency shifts, only requires the analyte to resonator mass ratio between 0.001 and 0.02.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10302 - Condensed matter physics (including formerly solid state physics, supercond.)
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Sensors and Actuators B - Chemical
ISSN
0925-4005
e-ISSN
0925-4005
Volume of the periodical
353
Issue of the periodical within the volume
Feb
Country of publishing house
CH - SWITZERLAND
Number of pages
9
Pages from-to
131062
UT code for WoS article
000744546700004
EID of the result in the Scopus database
2-s2.0-85119903426