Self-assembled nanoscale materials for neuronal regeneration: a focus on BDNF Protein and nucleic acid biotherapeutic delivery
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F22%3A00567933" target="_blank" >RIV/68378271:_____/22:00567933 - isvavai.cz</a>
Result on the web
<a href="https://hdl.handle.net/11104/0339215" target="_blank" >https://hdl.handle.net/11104/0339215</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/nano12132267" target="_blank" >10.3390/nano12132267</a>
Alternative languages
Result language
angličtina
Original language name
Self-assembled nanoscale materials for neuronal regeneration: a focus on BDNF Protein and nucleic acid biotherapeutic delivery
Original language description
Enabling challenging applications of nanomedicine and precision medicine in the treatment of neurodegenerative disorders requires deeper investigations of nanocarrier-mediated biomolecular delivery for neuronal targeting and recovery. The successful use of macromolecular biotherapeutics (recombinant growth factors, antibodies, enzymes, synthetic peptides, cell-penetrating peptide–drug conjugates, and RNAi sequences) in clinical developments for neuronal regeneration should benefit from the recent strategies for enhancement of their bioavailability. We highlight the advances in the development of nanoscale materials for drug delivery in neurodegenerative disorders. The emphasis is placed on nanoformulations for the delivery of brain-derived neurotrophic factor (BDNF) using different types of lipidic nanocarriers (liposomes, liquid crystalline or solid lipid nanoparticles) and polymer-based scaffolds, nanofibers and hydrogels.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10305 - Fluids and plasma physics (including surface physics)
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Nanomaterials
ISSN
2079-4991
e-ISSN
2079-4991
Volume of the periodical
12
Issue of the periodical within the volume
13
Country of publishing house
CH - SWITZERLAND
Number of pages
27
Pages from-to
2267
UT code for WoS article
000825633500001
EID of the result in the Scopus database
2-s2.0-85133126156