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Self-assembled nanoscale materials for neuronal regeneration: a focus on BDNF Protein and nucleic acid biotherapeutic delivery

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F22%3A00567933" target="_blank" >RIV/68378271:_____/22:00567933 - isvavai.cz</a>

  • Result on the web

    <a href="https://hdl.handle.net/11104/0339215" target="_blank" >https://hdl.handle.net/11104/0339215</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.3390/nano12132267" target="_blank" >10.3390/nano12132267</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Self-assembled nanoscale materials for neuronal regeneration: a focus on BDNF Protein and nucleic acid biotherapeutic delivery

  • Original language description

    Enabling challenging applications of nanomedicine and precision medicine in the treatment of neurodegenerative disorders requires deeper investigations of nanocarrier-mediated biomolecular delivery for neuronal targeting and recovery. The successful use of macromolecular biotherapeutics (recombinant growth factors, antibodies, enzymes, synthetic peptides, cell-penetrating peptide–drug conjugates, and RNAi sequences) in clinical developments for neuronal regeneration should benefit from the recent strategies for enhancement of their bioavailability. We highlight the advances in the development of nanoscale materials for drug delivery in neurodegenerative disorders. The emphasis is placed on nanoformulations for the delivery of brain-derived neurotrophic factor (BDNF) using different types of lipidic nanocarriers (liposomes, liquid crystalline or solid lipid nanoparticles) and polymer-based scaffolds, nanofibers and hydrogels.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10305 - Fluids and plasma physics (including surface physics)

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2022

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Nanomaterials

  • ISSN

    2079-4991

  • e-ISSN

    2079-4991

  • Volume of the periodical

    12

  • Issue of the periodical within the volume

    13

  • Country of publishing house

    CH - SWITZERLAND

  • Number of pages

    27

  • Pages from-to

    2267

  • UT code for WoS article

    000825633500001

  • EID of the result in the Scopus database

    2-s2.0-85133126156