Dynamical profile of connectivity changes of ictal epileptic networks
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21230%2F15%3A00233145" target="_blank" >RIV/68407700:21230/15:00233145 - isvavai.cz</a>
Result on the web
<a href="http://emps.exeter.ac.uk/media/universityofexeter/emps/research/dynamicsdays/ddays_exeter_abstracts_2015c.pdf" target="_blank" >http://emps.exeter.ac.uk/media/universityofexeter/emps/research/dynamicsdays/ddays_exeter_abstracts_2015c.pdf</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Dynamical profile of connectivity changes of ictal epileptic networks
Original language description
How seizures emerge from the abnormal dynamics of epileptic networks is still not clear. To elucidate the mechanisms of seizure initiation and progression it is necessary to understand the complex interaction between the individual network components andto identify the critical ones. Recent studies have demonstrated dynamical reconfiguration of functional network connectivity at the onset of the seizure, particularly within the seizure onset area. In this study we have explored the functional connectivity changes in invasive recordings from candidates of epilepsy surgery who were implanted with intracranial electrodes. For the purpose of this study we have developed a novel method based on multivariate directed transfer function (DTF) estimation, which is characterized by higher temporal resolution and improved statistical reliability when compared to traditional DTF techniques. Application to intracranial data enabled determination of the a priori probability of seizure connectivity
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
JA - Electronics and optoelectronics
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů