Feasibility study of direct cyclotron production of 227-Th
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21340%2F13%3A00214680" target="_blank" >RIV/68407700:21340/13:00214680 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Feasibility study of direct cyclotron production of 227-Th
Original language description
Aim Alpha emitting radiometals are promising tools for cancer treatment. One of them is 223Ra (half-life of 11.4 days) together with its mother nuclide, 227Th (half-life of 18.7 days).These nuclides can be obtained from 227Ac/227Th/223Ra generator produced via 226Ra(n,?)227Ra/227Ac reaction using nuclear reactor. This fact puts, however, high requirements on radiation stability of such a generator. Aim of this study was to develop alternative method for direct cyclotron production of 227Th via 226Ra(?,3n) reaction. Methods Cross-sections of the 226Ra(?,3n) reaction were adopted from TENDL-2012 library based on TALYS nuclear model code. Using these data, thick target yields of this reaction were calculated. Experimental verification of the predicted values was performed on a U-120M isochronous cyclotron of the Nuclear Physics Institute of the Academy of Science of the Czech Republic by irradiating single thin 226Ra targets. The targets were then analysed using alpha and gamma spectromet
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
CH - Nuclear and quantum chemistry, photo chemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/LK21310" target="_blank" >LK21310: Study of transmutation of Ra-226 and its separation from activation products</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů