HYDROXYAPATITE NANOPARTICLES LABELLED WITH 18F
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21340%2F18%3A00323779" target="_blank" >RIV/68407700:21340/18:00323779 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
HYDROXYAPATITE NANOPARTICLES LABELLED WITH 18F
Original language description
Hydroxyapatite based materials including nanoparticles (HAp-NPs) are widely used in medicine because of their stability in various biological media. The HAp-NPs also belong to promising drug carrier systems for medicinal radionuclides such as F-18 as the part of multipurpose theranostic system with other therapeutic and diagnostic radionuclides. HAp-NPs can show uptake by cancer tissue due to EPR effect, therefore diagnostic and therapy of the diseases are expected to be very accurate and beneficial. In vitro stability experiments have shown good stability of 18F-HAp-NPs nanoconstruct in a bovine blood serum and plasma (more than 90% of activity remained bound to the NPs in 7,5 hours).
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
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OECD FORD branch
10402 - Inorganic and nuclear chemistry
Result continuities
Project
<a href="/en/project/NV16-30544A" target="_blank" >NV16-30544A: New multistage nanodiagnostics for cancer imaging and prediction of antiangiogenic therapy efficacy</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů