Radiation sensitivity of biological systems, its modification by chemical modifiers and its quantitative evaluation

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21340%2F24%3A00377945" target="_blank" >RIV/68407700:21340/24:00377945 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1007/s10967-024-09611-6" target="_blank" >https://doi.org/10.1007/s10967-024-09611-6</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s10967-024-09611-6" target="_blank" >10.1007/s10967-024-09611-6</a>

Result language
angličtina
Original language name
Radiation sensitivity of biological systems, its modification by chemical modifiers and its quantitative evaluation
Original language description
Large number of sensitizers and protectors of cells, tissues, organs and organisms are being discussed in this review. Attention is paid to metals, nanoparticles or organic compounds as modifiers. They can modify the radiation sensitivity by 20-60%. In most cases, sensitization is caused by an increase in DNA damage or a decrease in the repair of radiation damage. The protection can be caused in many cases by repair of damaged DNA molecules, proteins or enzymes, or by reducing the ROS concentration. The most current research tasks in this area are formulated. A new quantitative and reproducible method of evaluating modifiers is discussed.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10400 - Chemical sciences

Project
<a href="/en/project/EF16_019%2F0000778" target="_blank" >EF16_019/0000778: Center for advanced applied science</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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