Neuron Adhesion on Diamond: Competition between Polymer Treatment and Surface Morphology
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F18%3A00339421" target="_blank" >RIV/68407700:21460/18:00339421 - isvavai.cz</a>
Alternative codes found
RIV/68378271:_____/18:00494905
Result on the web
<a href="https://doi.org/10.1002/adem.201800182" target="_blank" >https://doi.org/10.1002/adem.201800182</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/adem.201800182" target="_blank" >10.1002/adem.201800182</a>
Alternative languages
Result language
angličtina
Original language name
Neuron Adhesion on Diamond: Competition between Polymer Treatment and Surface Morphology
Original language description
The ability to form an efficient interface between material and neural cells is a crucial aspect for construction of neuroelectrodes. Diamond offers material characteristics that could, to a large extent, improve the performance of neuroelectrodes. The greatest advantage of diamond is a large variety of material and surface properties such as electrical conductivity, surface morphology, and surface chemistry. Such a variety of material characteristics can lead to various cellular responses. Here, the authors compare survival, adhesion, and neurite formation of primary neurons on diamond thin films of various morphologies and treatments with several types of polymers commonly used to enhance cell adhesion. The authors find that the variation of surface roughness of nanocrystalline diamond film when coated with polymer does not have a major influence on neuron survival or adhesion. The adhesion of neurons can be influenced by the selected type of polymer coating. High molecular weight of polyethylenimine results in lower viability, adhesion, and neurite formation. The addition of laminin to treated films do not lead to significant improvements in neuron adhesion and neurite development. Their findings emphasize the importance of the correct polymer treatment over morphological properties of diamond thin films as a material for forming interfaces with primary neurons.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
20506 - Coating and films
Result continuities
Project
<a href="/en/project/GA17-15319S" target="_blank" >GA17-15319S: Diamond based microelectrode arrays for dual mode neural recording</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Advanced Engineering Materials
ISSN
1438-1656
e-ISSN
1527-2648
Volume of the periodical
20
Issue of the periodical within the volume
9
Country of publishing house
DE - GERMANY
Number of pages
10
Pages from-to
1-10
UT code for WoS article
000445327200023
EID of the result in the Scopus database
2-s2.0-85053859063