Assessment of the thermal tissue models for the head and neck hyperthermia treatment planning

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F23%3A00366929" target="_blank" >RIV/68407700:21460/23:00366929 - isvavai.cz</a>

Result on the web

<a href="https://doi.org/10.1016/j.jtherbio.2023.103625" target="_blank" >https://doi.org/10.1016/j.jtherbio.2023.103625</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jtherbio.2023.103625" target="_blank" >10.1016/j.jtherbio.2023.103625</a>

Result language

angličtina

Original language name

Assessment of the thermal tissue models for the head and neck hyperthermia treatment planning

Original language description

Purpose To compare different thermal tissue models for head and neck hyperthermia treatment planning, and to assess the results using predicted and measured applied power data from clinical treatments. Methods Three commonly used temperature models from literature were analysed: “constant baseline”, “constant thermal stress” and “temperature dependent”. Power and phase data of 93 treatments of 20 head and neck patients treated with the HYPERcollar3D applicator were used. The impact on predicted median temperature T50 inside the target region was analysed with maximum allowed temperature of 44 °C in healthy tissue. The robustness of predicted T50 for the three models against the influence of blood perfusion, thermal conductivity and the assumed hotspot temperature level was analysed. Results We found an average predicted T50 of 41.0 ± 1.3 °C (constant baseline model), 39.9 ± 1.1 °C (constant thermal stress model) and 41.7 ± 1.1 °C (temperature dependent model). The constant thermal stress model resulted in the best agreement between the predicted power (P = 132.7 ± 45.9 W) and the average power measured during the hyperthermia treatments (P = 129.1 ± 83.0 W). Conclusion The temperature dependent model predicts an unrealistically high T50. The power values for the constant thermal stress model, after scaling simulated maximum temperatures to 44 °C, matched best to the average measured powers. We consider this model to be the most appropriate for temperature predictions using the HYPERcollar3D applicator, however further studies are necessary for developing of robust temperature model for tissues during heat stress.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

20201 - Electrical and electronic engineering

Project

<a href="/en/project/GA21-00579S" target="_blank" >GA21-00579S: Multiphysical Study of Superposition of Electromagnetic Waves in Human Head Model to Verify the Feasibility of Microwave Hyperthermia of Brain Tumors</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

JOURNAL OF THERMAL BIOLOGY

ISSN

0306-4565

e-ISSN

1879-0992

Volume of the periodical

115

Issue of the periodical within the volume

July

Country of publishing house

GB - UNITED KINGDOM

Number of pages

7

Pages from-to

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UT code for WoS article

001041320300001

EID of the result in the Scopus database

2-s2.0-85164437865