Susceptibility of Campylobacter jejuni to Organic Acids and Monoacylglycerols

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28110%2F10%3A63510080" target="_blank" >RIV/70883521:28110/10:63510080 - isvavai.cz</a>
Alternative codes found
RIV/67985904:_____/10:00348353 RIV/00027014:_____/10:#0001205
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Susceptibility of Campylobacter jejuni to Organic Acids and Monoacylglycerols
Original language description
Organic acids can be used as feed supplements or for treatment of poultry carcasses in processing plants. The antimicrobial activity of nineteen organic acids and two monoacylglycerols in cultures of Campylobacter jejuni CCM 6214(T) (ATCC 33560) was determined using a SYBR Green-based real-time PCR assay. The IC50 was a concentration at which only 50 % of a bacteria specific DNA sequence was amplified. Caprylic, capric and lauric acids were the most efficient antimicrobials among the compounds tested (IC50 a parts per thousand currency sign 0.1 mg/mL). In a weakly acidic environment (pH 5.5), the antimicrobial activity was more pronounced than at pH 6.5. At pH 5.5, oleic and fumaric acid also had clear antimicrobial activity, as did monocaprylin. The antimicrobial activity of acetic, butyric, stearic and succinic acid was low.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EE - Microbiology, virology
OECD FORD branch
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Project
<a href="/en/project/GD525%2F08%2FH060" target="_blank" >GD525/08/H060: Synbiotics and plant extracts in human and animal nutrition</a><br>
Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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