Thermoplastic modification of medical grade polyvinyl chloride with various antibiotics: Effect of antibiotic chemical structure on mechanical, antibacterial properties, and release activity
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28110%2F11%3A43865600" target="_blank" >RIV/70883521:28110/11:43865600 - isvavai.cz</a>
Alternative codes found
RIV/70883521:28610/11:43865600
Result on the web
<a href="http://dx.doi.org/10.1007/s00289-011-0474-3" target="_blank" >http://dx.doi.org/10.1007/s00289-011-0474-3</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00289-011-0474-3" target="_blank" >10.1007/s00289-011-0474-3</a>
Alternative languages
Result language
angličtina
Original language name
Thermoplastic modification of medical grade polyvinyl chloride with various antibiotics: Effect of antibiotic chemical structure on mechanical, antibacterial properties, and release activity
Original language description
Novel polymeric systems with antibacterial properties based on medical-grade polyvinyl chloride and antibiotics (Ampicillin, Minocycline, and Rifampicin) in the concentrations up to 1 wt% were prepared by thermoplastic compounding. Thermal stability of the antibiotics was corroborated by IR spectroscopy, X-ray diffraction, differential scanning calorimetry, and 1H nuclear magnetic resonance spectroscopy. The effect of chemical structure on mechanical properties of the prepared systems was determined bytensile testing measurements and correlated with optical microscopy observations. In vitro antibacterial properties of samples were determined by agar diffusion and adhesion test against Gramnegative and Gram-positive bacteria. Antibiotic release experiments in distilled water and physiological saline solution and follow-up detecting by Ultraviolet-Visible spectroscopy were carried out. A mathematical model was applied to evaluate the release kinetics of the antibiotics from prepared pol
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CD - Macromolecular chemistry
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Polymer Bulletin
ISSN
0170-0839
e-ISSN
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Volume of the periodical
67
Issue of the periodical within the volume
6
Country of publishing house
US - UNITED STATES
Number of pages
20
Pages from-to
997-1016
UT code for WoS article
000294201900006
EID of the result in the Scopus database
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