Atom transfer radical polymerization of 2-isopropenyl-2-oxazoline in solution and from the surface of carbonyl iron particles toward fabrication of a cytocompatible magneto-responsive hybrid filler

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28110%2F23%3A63569218" target="_blank" >RIV/70883521:28110/23:63569218 - isvavai.cz</a>

Alternative codes found

RIV/70883521:28610/23:63569218

Result on the web

<a href="https://pubs.acs.org/doi/10.1021/acs.macromol.3c00400" target="_blank" >https://pubs.acs.org/doi/10.1021/acs.macromol.3c00400</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1021/acs.macromol.3c00400" target="_blank" >10.1021/acs.macromol.3c00400</a>

Result language

angličtina

Original language name

Atom transfer radical polymerization of 2-isopropenyl-2-oxazoline in solution and from the surface of carbonyl iron particles toward fabrication of a cytocompatible magneto-responsive hybrid filler

Original language description

Atom transfer radical polymerization (ATRP) of 2-isopropenyl-2-oxazoline was optimized both in solution and initiated from carbonyl iron (CI) particle surface (SI-ATRP) in order to obtain polymers with well-defined molar mass and narrow dispersity. The polymerization procedure was thoroughly investigated by size exclusion chromatography and H-1 NMR and optimized from the point of view type of initiator, ligand, copper catalyst, and solvent. Finally, the poly-(2-isopropenyl-2-oxazoline)(PIPOx) with controlled molar masses up to 20,000 g/mol and dispersity in the range of 1.2-1.5 were successfully prepared, while high conversions could be reached. Polymerization conditions using halogen exchange leading to well-defined PIPOx were also developed and used for SI-ATRP. SI-ATRP was finally applied for synthesis of magnetic CI-PIPOx core-shell particles with two various molar masses of the grafted PIPOx. Finally, as a proof of applicability of such hybrid particles, the particles were dispersed in the phosphate buffer saline and glycerol to obtain the magnetorheological fluid with blood-like characteristics. Magnetorheological and cytotoxicity investigations proved that non-cytotoxic CI-PIPOx core-shell particles provided the system with sufficient yield stress values to act as an embolization agent.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10404 - Polymer science

Project

—

Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Macromolecules

ISSN

0024-9297

e-ISSN

—

Volume of the periodical

56

Issue of the periodical within the volume

11

Country of publishing house

US - UNITED STATES

Number of pages

9

Pages from-to

3904-3912

UT code for WoS article

001010456800001

EID of the result in the Scopus database

2-s2.0-85163363888