Carboxymethylated and sulfated furcellaran from furcellaria lumbricalis and its immobilization on PLA scaffolds

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28610%2F24%3A63579098" target="_blank" >RIV/70883521:28610/24:63579098 - isvavai.cz</a>

Result on the web

<a href="https://www.mdpi.com/2073-4360/16/5/720" target="_blank" >https://www.mdpi.com/2073-4360/16/5/720</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/polym16050720" target="_blank" >10.3390/polym16050720</a>

Result language

angličtina

Original language name

Carboxymethylated and sulfated furcellaran from furcellaria lumbricalis and its immobilization on PLA scaffolds

Original language description

This study involved the creation of highly porous PLA scaffolds through the porogen/leaching method, utilizing polyethylene glycol as a porogen with a 75% mass ratio. The outcome achieved a highly interconnected porous structure with a thickness of 25 mu m. To activate the scaffold&apos;s surface and improve its hydrophilicity, radiofrequency (RF) air plasma treatment was employed. Subsequently, furcellaran subjected to sulfation or carboxymethylation was deposited onto the RF plasma treated surfaces with the intention of improving bioactivity. Surface roughness and water wettability experienced enhancement following the surface modification. The incorporation of sulfate/carboxymethyl group (DS = 0.8; 0.3, respectively) is confirmed by elemental analysis and FT-IR. Successful functionalization of PLA scaffolds was validated by SEM and XPS analysis, showing changes in topography and increases in characteristic elements (N, S, Na) for sulfated (SF) and carboxymethylated (CMF). Cytocompatibility was evaluated by using mouse embryonic fibroblast cells (NIH/3T3).

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10404 - Polymer science

Project

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Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Polymers

ISSN

2073-4360

e-ISSN

2073-4360

Volume of the periodical

16

Issue of the periodical within the volume

5

Country of publishing house

CH - SWITZERLAND

Number of pages

15

Pages from-to

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UT code for WoS article

001183421200001

EID of the result in the Scopus database

2-s2.0-85187799282