Composite Injectable Hydrogels for Bone Regeneration: The Synergistic Effect of Polypyrrole and BMP-2

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28610%2F25%3A63594458" target="_blank" >RIV/70883521:28610/25:63594458 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Composite Injectable Hydrogels for Bone Regeneration: The Synergistic Effect of Polypyrrole and BMP-2
Original language description
Bone defects, especially critical-size defects, present a significant challenge in orthopedic medicine, resulting in agrowing interest in advanced biomaterials that can promote bone regeneration and possess anti-inflammatory properties.Shear-thinning hydrogels are particularly promising biomaterials for this purpose, as they can mimic the naturalextracellular matrix, support cell proliferation and differentiation, be injected into irregular defect sites, and adapt to thedefect shape. In this study, we developed a chitosan/polypyrrole composite hydrogel with BMP-2-loaded microspheresfor the treatment of critical-size bone defects.
Czech name
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Czech description
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Project
<a href="/en/project/GA24-11534S" target="_blank" >GA24-11534S: Conductive (bio)polymer composites with covalently anchored polypyrrole for biomedical applications</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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