Cytotoxicity and antioxidative effects of herbal and fruit extracts in vitro

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F75010330%3A_____%2F14%3A00010598" target="_blank" >RIV/75010330:_____/14:00010598 - isvavai.cz</a>
Result on the web
<a href="http://link.springer.com/article/10.1007%2Fs11483-014-9349-0" target="_blank" >http://link.springer.com/article/10.1007%2Fs11483-014-9349-0</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s11483-014-9349-0" target="_blank" >10.1007/s11483-014-9349-0</a>

Result language
angličtina
Original language name
Cytotoxicity and antioxidative effects of herbal and fruit extracts in vitro
Original language description
The aim of this work was study the cytotoxicity and antioxidative activity of eight extracts with hypothetical antioxidative influence in vitro. To further elucidate of a possible role of herbals/fruit extracts on cell protection was used on the healthyand UV-A damaged mouse fibroblast cells. The cell viability was detect using MTT assay. Kinetic production of reactive oxygen species, identification of cell death, cell cycle and gne expression C-FOS were measured. Intracellular and mitochondrial transmembrane potential was evaluated with JC-1 fluorescent probe. Comet assay was amployed to detect the UV-A induced DNA damage.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FM - Hygiene
OECD FORD branch
—

Project
<a href="/en/project/NT14060" target="_blank" >NT14060: Nanotechnologies and consumer health risks</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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