Horizontal transfer of mitochondria between mammalian cells: beyond co-culture approaches

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F86652036%3A_____%2F16%3A00469023" target="_blank" >RIV/86652036:_____/16:00469023 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.gde.2016.04.003" target="_blank" >http://dx.doi.org/10.1016/j.gde.2016.04.003</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.gde.2016.04.003" target="_blank" >10.1016/j.gde.2016.04.003</a>

Result language
angličtina
Original language name
Horizontal transfer of mitochondria between mammalian cells: beyond co-culture approaches
Original language description
Current dogma holds that genes are the property of individual mammalian cells and partition between daughter cells during cell division. However, and rather unexpectedly, recent research has demonstrated horizontal cell-to-cell transfer of mitochondria and mitochondrial DNA in several mammalian cell culture systems. Furthermore, unequivocal evidence that mitochondrial DNA transfer occurs in vivo has now been published. While these studies show horizontal transfer of mitochondrial DNA in pathological settings, it is also possible that intercellular mitochondrial transfer is a fundamental physiological process with a role in development and tissue homeostasis.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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