Heme oxygenase is not involved in the anti-proliferative effects of statins on pancreatic cancer cells

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F86652036%3A_____%2F16%3A00473134" target="_blank" >RIV/86652036:_____/16:00473134 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/16:10324349 RIV/00216208:11120/16:43911609 RIV/00064173:_____/16:N0000011 RIV/00064165:_____/16:10324349 RIV/60461373:22330/16:43901850
Result on the web
<a href="http://dx.doi.org/10.1186/s12885-016-2343-9" target="_blank" >http://dx.doi.org/10.1186/s12885-016-2343-9</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1186/s12885-016-2343-9" target="_blank" >10.1186/s12885-016-2343-9</a>

Result language
angličtina
Original language name
Heme oxygenase is not involved in the anti-proliferative effects of statins on pancreatic cancer cells
Original language description
Background: Pancreatic cancer is recognized as one of the most fatal tumors due to its aggressiveness and resistance to therapy. Statins were previously shown to inhibit the proliferation of cancer cells via various signaling pathways. In healthy tissues, statins activate the heme oxygenase pathway, nevertheless the role of heme oxygenase in pancreatic cancer is still controversial. The aim of this study was to evaluate, whether anti-proliferative effects of statins in pancreatic cancer cells are mediated via the heme oxygenase pathway.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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