Evolutionary conservation of maternal RNA localization in fishes and amphibians revealed by TOMO-Seq

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F86652036%3A_____%2F22%3A00559401" target="_blank" >RIV/86652036:_____/22:00559401 - isvavai.cz</a>
Alternative codes found
RIV/60076658:12520/22:43904521 RIV/00216208:11310/22:10448332
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S0012160622001300?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0012160622001300?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.ydbio.2022.06.013" target="_blank" >10.1016/j.ydbio.2022.06.013</a>

Result language
angličtina
Original language name
Evolutionary conservation of maternal RNA localization in fishes and amphibians revealed by TOMO-Seq
Original language description
Asymmetrical localization of biomolecules inside the egg, results in uneven cell division and establishment of many biological processes, cell types and the body plan. However, our knowledge about evolutionary conservation of localized transcripts is still limited to a few models. Our goal was to compare localization profiles along the animal-vegetal axis of mature eggs from four vertebrate models, two amphibians (Xenopus laevis, Ambystoma mexicanum) and two fishes (Acipenser ruthenus, Danio rerio) using the spatial expression method called TOMO-Seq. We revealed that RNAs of many known important transcripts such as germ layer determinants, germ plasm factors and members of key signalling pathways, are localized in completely different profiles among the models. It was also observed that there was a poor correlation between the vegetally localized transcripts but a relatively good correlation between the animally localized transcripts. These findings indicate that the regulation of embryonic development within the animal kingdom is highly diverse and cannot be deduced based on a single model.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10608 - Biochemistry and molecular biology

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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