Mean value of LET for oncogenic effects of radon and its progeny
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F86652052%3A_____%2F19%3AN0000074" target="_blank" >RIV/86652052:_____/19:N0000074 - isvavai.cz</a>
Result on the web
<a href="https://academic.oup.com/rpd/article/186/2-3/159/5658465" target="_blank" >https://academic.oup.com/rpd/article/186/2-3/159/5658465</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/rpd/ncz194" target="_blank" >10.1093/rpd/ncz194</a>
Alternative languages
Result language
angličtina
Original language name
Mean value of LET for oncogenic effects of radon and its progeny
Original language description
The topic of the article is to define the average value of linear energy transfer (LET) for carcinogenic effects of radon progeny. The microdosimetric model of boundary specific energy is used. It follows that the effect at high LET should decrease approximately with the third power of LET. This is verified by the analysis of the relationship between radiation effects ratio and LET in published experiments with oncogenic transformation of mammalian cells irradiated with the monoenergetic alpha particles. If these cells are exposed with the radon irradiator, our analysis leads us to conclude that the oncogenic effect of radon progeny is comparable to that of alpha particles with a LET of 75 keV/μm. It is about a quarter lower than the LET value, where the effect of the monoenergetic alpha particles reaches its maximum level. Some implications for lung cancer due to radon inhalation may also be carefully examined.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30304 - Public and environmental health
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Radiation Protection Dosimetry
ISSN
0144-8420
e-ISSN
1742-3406
Volume of the periodical
186
Issue of the periodical within the volume
2-3
Country of publishing house
GB - UNITED KINGDOM
Number of pages
4
Pages from-to
159-162
UT code for WoS article
000530582200003
EID of the result in the Scopus database
2-s2.0-85082779757