Vše

Co hledáte?

Vše
Projekty
Výsledky výzkumu
Subjekty

Rychlé hledání

  • Projekty podpořené TA ČR
  • Významné projekty
  • Projekty s nejvyšší státní podporou
  • Aktuálně běžící projekty

Chytré vyhledávání

  • Takto najdu konkrétní +slovo
  • Takto z výsledků -slovo zcela vynechám
  • “Takto můžu najít celou frázi”
CS
ČeštinaEnglish

Filtry

1 444 (0,075s) •

Projekt

Modeling activation of human calcium release-activated channels. (GJ19-20728Y)

of the calcium stores upon depletion. CRAC is the combination of one channel located of CRAC channels. We propose here to investigate the calcium-sensor protein from CRACCalcium ions are primarily used by...

Physical chemistry

  • 2019 - 2021
    • •
  • 3 479 tis. Kč
    • •
  • 3 479 tis. Kč
    • •
  • GA ČR
Projekt

Neurohumoral control of calcium influx nifedipine-sensitive component of blood pressure in experimental hypertension (IAA500110902)

) and nitric oxide (NO) in the control of calcium influx through nifedipine-sensitive voltage-dependent calcium channels (VDCC) in blood vessels of normotensive and hypertensive rats. Our parallel in vivo and in vitro exper...

ED - Fyziologie

  • 2009 - 2011
    • •
  • 4 157 tis. Kč
    • •
  • 4 157 tis. Kč
    • •
  • AV ČR
Projekt

Pathophysiology of T-type calcium channels in diabetic neuropathy (7AMB15FR015)

of T-type channels with SNARE proteins and investigate the functional importance of T-type channel / SNARE complexes in the synaptic physiology of nociceptive of T-type Ca2+ channel / SNAREs interaction. Aim #2: Formation ...

FH - Neurologie, neurochirurgie, neurovědy

  • 2015 - 2016
    • •
  • 108 tis. Kč
    • •
  • 108 tis. Kč
    • •
  • MŠMT
Projekt

Alpha2delta auxiliary subunit of voltage-dependent Ca2+ channels as a novel therapeutic target for the treatment of hypertension (GP14-16225P)

) and elevated calcium current in vascular smooth muscle cells (VSMC). Voltage-dependent calcium channels (VDCC) play an important role in both increased sympathetic surface localization of these channels and hence...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2014 - 2016
    • •
  • 2 919 tis. Kč
    • •
  • 2 919 tis. Kč
    • •
  • GA ČR
Projekt

Fantastic CNGC channels and how to open them (GA25-16449S)

Cyclic nucleotide gated channels (CNGCs) are tetrameric plasma membrane channels responsible for various calcium responses, such as rapid auxin response) proteins are essential for the functioning of multiple CNGC chann...

Cell biology

  • 2025 - 2027
    • •
  • 9 834 tis. Kč
    • •
  • 9 834 tis. Kč
    • •
  • GA ČR
Projekt

Pathophysiology of T-type calcium channels in diabetic neuropathy (GA15-13556S)

in general elusive, recent reports indicate a key role of T-type calcium channels in peripheral nociception. In addition, an increase in T-type channel expression pathways by which T-type channels cause neuropathy...

CE - Biochemie

  • 2015 - 2017
    • •
  • 7 216 tis. Kč
    • •
  • 7 216 tis. Kč
    • •
  • GA ČR
Projekt

Physio(patho)logy of T-type calcium channels in motor neuron function (GA22-23242S)

that CACNA1H encoding for Cav3.2 T-type Ca2+ channels may represent a risk factor for the disease. However, the pathophysiological role of T-type channels in motor neurons has channels in the functioning of motor neurons a...

Neurosciences (including psychophysiology)

  • 2022 - 2024
    • •
  • 7 472 tis. Kč
    • •
  • 7 472 tis. Kč
    • •
  • GA ČR
Projekt

Understanding different aspects of structure and function of cation translocation systems. (LTC17069)

3D structural models of all human Orai family members; most probable multimeric state of the humanOrai channel; amino-acids regulating gating; quantification of Ca2+ binding to the unique, extracellular accumulating region CAR; divergent arc...

BO - Biofyzika

  • 2017 - 2019
    • •
  • 2 083 tis. Kč
    • •
  • 2 083 tis. Kč
    • •
  • MŠMT
Projekt

Electrical excitability and calcium signaling in anterior pituitary cells (GA305/07/0681)

-gated channels and cAMP-gated channels. Patch clamp recording and cell calcium activity are still unknown. Here we plan to study membrane receptors and ionic channels of receptors and channels at molecula...

ED - Fyziologie

  • 2007 - 2011
    • •
  • 4 865 tis. Kč
    • •
  • 4 865 tis. Kč
    • •
  • GA ČR
Projekt

Mechanism of the inhibitory effect of melatonin on GnRH-induced (Ca2+), increase and LH release in neonatal rat gonadotrophs (GA309/97/0513)

by blocking calcium influx through voltage-sensitive channels, as well as by blocking mobilization of calcium. The melatonin inhibition of Ca2+ influx through voltage-sensitive channels may involve membrane potent...

ED - Fyziologie

  • 1997 - 1999
    • •
  • 3 938 tis. Kč
    • •
  • 2 989 tis. Kč
    • •
  • GA ČR
  • 1 - 10 z 1 444