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3 962 (0,162s)

Projekt

The detection of biofilm as a factor of virulence within complex diagnostics of yeast blood stream infections (NR7980)

) will be studied. The values of minimal inhibitory concentration (MIC) and minimal biofilm inhibitory concentration (MBIC) of different antomycotics will be determined......

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2004 - 2006
  • 2 721 tis. Kč
  • 2 681 tis. Kč
  • MZ
Projekt

Effect of boar seminal immunosuppressive fraction on the development of some model autoimmune diseases (GA303/01/0615)

We have demonstrated lately that boar seminal immunosuppressive fraction (ISF) decreased lymphocyte number and inhibited antibody response and immunoglobulin concentrations trough its binding to lymphocytes. In this project, we aim ...

CE - Biochemie

  • 2001 - 2003
  • 4 209 tis. Kč
  • 2 361 tis. Kč
  • GA ČR
Projekt

*Research and development of medical devices based on nanomaterials (FR-TI2/205)

*Nanotechnology allows change properties of existing products, or to produce new products. Their properties are unattainable by classical methods, while minimizing the volumes and concentrations of active substances. The project is ...

FR - Farmakologie a lékárnická chemie

  • 2010 - 2013
  • 17 014 tis. Kč
  • 12 990 tis. Kč
  • MPO
Projekt

The study of physical and chemical characteristics of microparticles in emissions (TA02020004)

Minimization of emmissions of total suspended particles - TSP at large industrial sources and evaluation of possibility of technological solutions in relationship with the real contribution to decrease of PM10 concentration in the a...

JE - Nejaderná energetika, spotřeba a užití energie

  • 2012 - 2015
  • 15 902 tis. Kč
  • 9 100 tis. Kč
  • TA ČR
Projekt

Modulation of nuclear receptors for steroid hormones by plant hormone derivatives (NT11060)

The aim of the project is 1) to assess the influence of the brassinosteroids on cell viability and proliferation and 2) to determine concentrations inducing 50% cell viability inhibition (IC50) or stimulating concentrations...

FD - Onkologie a hematologie

  • 2010 - 2013
  • 2 854 tis. Kč
  • 2 854 tis. Kč
  • MZ
Projekt

Polymorphism of genes for HLA-G and KIR as a possible marker of female fertility disorders - failure of embryotransfer and repeated pregnancy loss. (NR9135)

in periimplantation decidua. Leukemia inhibiting factor (LIF) is pleiotropic cytokine. Increased concentration of this cytokine in periimplantation decidua inhibits maternal immunity......

FK - Gynekologie a porodnictví

  • 2007 - 2009
  • 5 270 tis. Kč
  • 5 113 tis. Kč
  • MZ
Projekt

Anti-inflammatory activity of plant quinones (GP525/09/P528)

Scope of this project is the study inhibition of cyclooxygenases (COXs. Screening of selected plant quinones for COX-1, COX-2 and 5-LOX inhibition and impact solving. For perspective compounds inhibitory concentrations (IC5...

GM - Potravinářství

  • 2009 - 2011
  • 1 219 tis. Kč
  • 1 219 tis. Kč
  • GA ČR
Projekt

The modulating influence of NO in the signal pathways controlling hormonal secretion, in the development of experimental diabetes and protein glycation (GA311/98/P089)

inhibit iodine organification and the growth of thyrocytes in vitro. The NO-synthase inhibitor, methylene blue, partially inhibits estrogen - induced hypertrophic reaction diabetes in rats and decreases the concentration o...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 1998 - 2000
  • 932 tis. Kč
  • 624 tis. Kč
  • GA ČR
Projekt

Induction of hyperbilirubinemia by plant flavonolignans as a new tool for the prevention of increased oxidative stress (NV16-27317A)

concentrations are in negative relationship with the risk of oxidative stress-mediated each micromolar increase of its serum concentrations. The major enzymes in the heme by HMOX1 induction and simultaneous partial UGT1A1 inhib...

CE - Biochemie

  • 2016 - 2019
  • 9 111 tis. Kč
  • 9 111 tis. Kč
  • MZ
Projekt

DHFR- and non-DHFR-mediated effects of methotrexate on cellular level a study on cell lines derived from pediatric solid tumors (NT14327)

of the MTX action: (1) inhibition of nucleic acid synthesis (detection of changes in cell) inhibition of DNA methylation (detection of changes in methylation of genes of the RAR signaling pathway in relation to the ATRA-induced cel...

FG - Pediatrie

  • 2013 - 2015
  • 5 195 tis. Kč
  • 5 195 tis. Kč
  • MZ
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