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617 (0,072s) •

Projekt

Novel methylation of Hexim1 and cyclin composition of positive trancription elongation factor b (P-TEFb) regulate kinase activity of cdk9 (ME09047)

Our preliminary experiments demonstrate that in eukaryotic cells novel posttranslational modification of proteins, methylation of glutamic acid (E), found in the P-TEFb binding domain of Hexim1, directs association of P-

EB - Genetika a molekulární biologie

  • 2009 - 2012
    • •
  • 3 247 tis. Kč
    • •
  • 2 224 tis. Kč
    • •
  • MŠMT
Projekt

Function of Positive Transcription Elongation Factor b (P-TEFb) in cardiac hypertrophy (GA301/09/1832)

transcription factor called Positive Transcription Elongation Factor b (P-TEFb) directing differences between signaling pathways upstream of activation of P-TEFb leading to either of specific post-translational mo...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2009 - 2011
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  • 3 186 tis. Kč
    • •
  • 3 186 tis. Kč
    • •
  • GA ČR
Projekt

The novel isoform of cyclin K is a partner of cdk12 kinase regulating eukaryotic transcription and alternative splicing (GAP305/11/1564)

The transcription of protein coding genes is executed by RNA Polymerase II (RNAPII). Phosphorylation status of the C-terminal domain (CTD) of the large subunit of RNAP II is crucial for the regulation of transcription and co-transcriptional pre-mRNA ...

EB - Genetika a molekulární biologie

  • 2011 - 2013
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  • 5 282 tis. Kč
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  • 5 089 tis. Kč
    • •
  • GA ČR
Projekt

The role of Cdk12 and C-terminal domain of RNA polymerase II in transcription-coupled genome instability (GA14-09979S)

RNA polymerase II (RNAPII) directs transcription of protein-coding genes. It contains a C-terminal domain (CTD) with repeats of heptapeptide YSPTSPS where individual serines (Ser) get phosphorylated. The phosphorylation status of the CTD regulates tr...

EB - Genetika a molekulární biologie

  • 2014 - 2016
    • •
  • 7 155 tis. Kč
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  • 7 155 tis. Kč
    • •
  • GA ČR
Projekt

*Line of pistols equipped with plastic (polymer) frame - CZ P 010, 020, 030. (FI-IM/141)

*Line of pistols equipped with plastic (polymer) frame - CZ P 010, 020, 030....

JY - Střelné zbraně, munice, výbušniny, bojová vozidla

  • 2004 - 2007
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  • 11 265 tis. Kč
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  • 2 815 tis. Kč
    • •
  • MPO
Projekt

Membrane systems and their applications (GP201/09/P075)

to a computing models inspirited by biochemistry of structure of cells called P systems. Since 1998, where the P systems were introduced by Gheorghe Păun, the various types try to connect the theory of P systems with the t...

IN - Informatika

  • 2009 - 2011
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  • 434 tis. Kč
    • •
  • 434 tis. Kč
    • •
  • GA ČR
Projekt

Photoelectrochemical evolution of hydrogen from aqueous media on P- InP, P- GaP and In0.5 Ga 0.5 P cathodes (GA104/95/0034)

CF - Fyzikální chemie a teoretická chemie

  • 1995 - 1997
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  • 2 181 tis. Kč
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  • 2 181 tis. Kč
    • •
  • GA ČR
Projekt

Influence of P-glycoprotein induction on pharmacokinetics (GP305/01/D089)

P-glycoprotein (P-gp) is a membrane ATP-dependent transporter that is able to transport a wide range of lipophilic drugs out of the cell. Transport by P-glycoprotein, because P-gp is not only the cause of multidrug...

FR - Farmakologie a lékárnická chemie

  • 2001 - 2004
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  • 1 319 tis. Kč
    • •
  • 696 tis. Kč
    • •
  • GA ČR
Projekt

Organization of the international workshop "Jets in p+p and heavy-ion collisions" (ME10016)

The aim of this project is to organize at FNSPE CTU Prague in collaboration with Yale University and Lawrence Berkeley National Laboratory an international workshop dedicated to jet physics in p+p and heavy-ion collisions.......

BG - Jaderná, atomová a molekulová fyzika, urychlovače

  • 2010 - 2010
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  • 236 tis. Kč
    • •
  • 236 tis. Kč
    • •
  • MŠMT
Projekt

Innovative control of phosphorus status in agricultural soils from ecological aspects of frugal using natural resources (QH82281)

production for rising up world population. P-resources of the Earth for an economical production P-fertilizers are limited only for several decades of years. Any of soil reserve and P-fertilizers, and recycling P ...

DF - Pedologie

  • 2008 - 2012
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  • 4 378 tis. Kč
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  • 4 157 tis. Kč
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  • MZe
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