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198 (0,085s)

Projekt

Creating of prognostic panel in patients with monoclonal gammopathy of undetermined significance with a target to prevent the risk of malignant transformation. (NS10406)

Development of a prognostic panel for patients with monoclonal gammopathy of unknown significance using conventional risk factors for malignant transformation as well as novel parameters based on genomic and flowcytometric analysis....

FD - Onkologie a hematologie

  • 2009 - 2011
  • 9 450 tis. Kč
  • 9 441 tis. Kč
  • MZ
Projekt

The significance of the analysis of the pairs of immunoglobulin heavy/light chains by Hevylite TM in monoclonal gammopathy of undetermined significance and multiple myeloma (NT12451)

Assessment of the significance of serum levels of the pairs of heavy/light immunoglobulin chains including the HLC kappa/lambda index using the Hevylite TM method in MGUS and multiple myeloma. Comparison of the HLC method with gel and immunofixation ...

FD - Onkologie a hematologie

  • 2011 - 2015
  • 6 254 tis. Kč
  • 6 254 tis. Kč
  • MZ
Projekt

International centre for research and training in hematooncology and monoclonal gammopathy (EE2.3.20.0046)

The aim is to deepen mutual cooperation and sharing of know-how with other European centers for research on monoclonal gammopathy by organizing regular educational seminars, workshops and international conferences. At the same time ...

FD - Onkologie a hematologie

  • 2011 - 2014
  • 21 114 tis. Kč
  • 21 114 tis. Kč
  • MŠMT
Projekt

Phenotype feature of B cells and plasma cells and its association with malignant transformation in monoclonal gammopathies (NS10408)

Flow cytometric analysis of B cells and plasma cells subtypes in healthy volunteers and monoclonal gammopathy patients. Identification of clonal cells in compartment of plasma cells or B cells and their purification for other purpos...

FD - Onkologie a hematologie

  • 2009 - 2011
  • 3 582 tis. Kč
  • 3 582 tis. Kč
  • MZ
Projekt

Assessment of free light chains as auxiliary marker for the evaluation of prognosis and of the response to treatment in patients with multiple myeloma and with monoclonal gammopathy of unknown (NS10387)

in monoclonal gammopathy of undetermined significance. Use of FLC for early prediction...

FD - Onkologie a hematologie

  • 2009 - 2011
  • 6 311 tis. Kč
  • 6 311 tis. Kč
  • MZ
Projekt

Comparison of dendritic cells from healthy volunteers, patients with monoclonal gammopathy and multiple myeloma according to their functional properties (NR8081)

The aim of project is analysis of function state of dendritic cells generated from patients with multiple myeloma and monoclonal gammopathy according to healthy volunteers. The aim of project is finding of possible defects of dendri...

EC - Imunologie

  • 2004 - 2006
  • 1 367 tis. Kč
  • 1 315 tis. Kč
  • MZ
Projekt

Analysis of Clonal Plasma Cells Progenitors in Monoclonal Gammopathies (GAP304/10/1395)

Detailed study of heterogeneous subpopulations of myeloma cells and their precursors/progenitors in monoclonal gammopathy patients can lead to identification and characterisation of myeloma stem cells. Using polychromatic flow cytom...

FD - Onkologie a hematologie

  • 2010 - 2015
  • 8 037 tis. Kč
  • 8 037 tis. Kč
  • GA ČR
Projekt

Multiparametric flow cytometry in study of malignant plasma cells pathophysiology (GP301/09/P457)

phenotypic profile in subjects with monoclonal gammopathy. The pathophysiology of plasma transformation in monoclonal gammopathy of undetermined significance. This project can determination of diagnose, assessment...

FD - Onkologie a hematologie

  • 2009 - 2011
  • 1 200 tis. Kč
  • 1 200 tis. Kč
  • GA ČR
Projekt

Complex Panel for Monoclonal Gammopathies Genetic Screening (TQ03000338)

The project's primary goal is to establish a complex methodology (genetic panel), enabling to obtain information about genetic changes in the DNA of aberrant cells, relevant to the prognosis and the treatment decision for patients with monoclonal...

Medical laboratory technology (including laboratory samples analysis; diagnostic technologies) (Biomaterials to be 2.9 [physical characteristics of living material as related to medical implants, devices, sensors])

  • 2024 - 2025
  • 4 630 tis. Kč
  • 3 962 tis. Kč
  • TA ČR
Projekt

Signalling pathways in myeloma bone disease (NT14393)

The aim of the project is to improve diagnostics and monitoring of myeloma bone disease with specification of the indications of anti-resorption therapy. For the assessment of convenient cytokines and chemokines we will use accessible biological mate...

FD - Onkologie a hematologie

  • 2013 - 2015
  • 3 036 tis. Kč
  • 3 036 tis. Kč
  • MZ
  • 1 - 10 z 198