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5 305 (0,093s) •

Projekt

Role of the pore-forming activity in adenylate cyclase toxin action and Bordetella virulence (GAP302/12/0460)

. In parallel, CyaA permeabilizes cellular membrane by forming oligomeric cation-selective pores. The objective of this proposal is to decipher the role of the pore-forming virulence. We shall characterize the prop...

CE - Biochemie

  • 2012 - 2016
    • •
  • 15 307 tis. Kč
    • •
  • 15 307 tis. Kč
    • •
  • GA ČR
Projekt

Perforated phase boundary. self-assembled array of pore-forming compuonds with controlled size of pores on liquid-liquid phase boundary (GA203/97/0350)

ligands for various cations and anions possessing the ability to form self-assembled two-dimensional oriented network of molecular pores at two immiscible liquids of polymeric materials with adjustable pore size. There are...

CC - Organická chemie

  • 1997 - 1999
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  • 3 747 tis. Kč
    • •
  • 2 210 tis. Kč
    • •
  • GA ČR
Projekt

Oxidative Stress and Pore-Forming Zymocines Effect on Transport Functions of the Yeast Plasma Membrane (IA52084)

CE - Biochemie

  • 1992 - 1994
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  • 0 tis. Kč
    • •
  • 0 tis. Kč
    • •
  • AV ČR
Projekt

Development of New Fluorescence Methods for the Characterization of Pores Formed by Antimicrobial Peptides (GAP208/10/1090)

of membrane pores. Since these pores are not stable structures and are smaller than of those pores for a specific AMP are missing. Our aim is to develop new methods for characterization of antimicrobial pores, bas...

CF - Fyzikální chemie a teoretická chemie

  • 2010 - 2012
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  • 2 162 tis. Kč
    • •
  • 2 162 tis. Kč
    • •
  • GA ČR
Projekt

Targeting and activity of RTX toxins of Gram-negative pathogens (GA22-01558S)

permeabilize cellular membrane by forming of cation-selective pores. Both toxins bind involved in membrane insertion and penetration of pore-forming RTX toxins in general-terminal part of RTX toxins in formation o...

Microbiology

  • 2022 - 2024
    • •
  • 9 762 tis. Kč
    • •
  • 9 762 tis. Kč
    • •
  • GA ČR
Projekt

Characterization of the activity and self-assembly of novel nanostructures and pore-forming peptides on model and native lipid membranes (LUC25110)

The primary goal of this project is to deepen the understanding of bioactive, antimicrobial, and pore-forming peptides' interactions with model and biological membranes, and pore formation, by examining peptides in simple l...

Biophysics

  • 2025 - 2028
    • •
  • 5 794 tis. Kč
    • •
  • 5 794 tis. Kč
    • •
  • MŠMT
Projekt

Influence of radiolysis and bacterial extremophiles on lifetime of the canister for deep geological repository (TK03010067)

properties of bentonite pore solution and stability and semiconductive properties of radiolysis on uniform corrosion rate and susceptibility to localised forms of corrosion of stainless steel. 3. The estimation of the influence of...

Nuclear related engineering; (nuclear physics to be 1.3);

  • 2020 - 2023
    • •
  • 9 989 tis. Kč
    • •
  • 7 957 tis. Kč
    • •
  • TA ČR
Projekt

Exploring the structure function relationship of membrane-pore-forming FGF2 oligomers - a single molecule approach (GC14-03141J)

in the PI(4,5)P2 dependent manner, and by forming a membrane pore it spans over the entire bilayer, and eventually forms a ternary complex with heparan sulfate membrane pores, that intermediate FGF2 membrane trans...

BO - Biofyzika

  • 2014 - 2016
    • •
  • 3 933 tis. Kč
    • •
  • 3 933 tis. Kč
    • •
  • GA ČR
Projekt

Porous Ceramics with Tailored Elasticity and Thermal Conductivity (GAP108/12/1170)

approaches (partial sintering, pore-forming agents, foaming) in a porosity range from, apart from traditional descriptors (porosity, pore size distribution), image-analysis-based descriptors containing information on p...

JH - Keramika, žáruvzdorné materiály a skla

  • 2012 - 2014
    • •
  • 2 165 tis. Kč
    • •
  • 2 165 tis. Kč
    • •
  • GA ČR
Projekt

Exploring the structure function relationship of membrane-pore-forming FGF2 oligomers - a single molecule approach (GC20-01401J)

to represent key intermediates of this process forming lipidic membrane pores...

Biophysics

  • 2020 - 2022
    • •
  • 4 953 tis. Kč
    • •
  • 4 616 tis. Kč
    • •
  • GA ČR
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