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Projekt

REM sleep behavior disorder – clinical presentation, disease course and its implications (NV16-28914A)

REM sleep behavior disorder (RBD) is characterized by dream enactment behavior associated with loss of REM sleep muscle atonia. Idiopathic form (iRBD) is recognized myoclonus and behavior in REM <...

FH - Neurologie, neurochirurgie, neurovědy

  • 2016 - 2019
  • 8 377 tis. Kč
  • 8 377 tis. Kč
  • MZ
Projekt

REM sleep behavior disorder predicting the risk of neurodegeneration (GA16-07879S)

Idiopathic REM sleep behavior disorder (iRBD) characterized by dream enactment behavior associated with loss of REM sleep muscle atonia is recognized as prodromal stage of neurodegenerative synucleinopathy...

FH - Neurologie, neurochirurgie, neurovědy

  • 2016 - 2020
  • 7 179 tis. Kč
  • 7 179 tis. Kč
  • GA ČR
Projekt

Smart Speech Biomarkers for Parkinson’s Disease and Other Synucleinopathies (NU20-08-00445)

preclinical stages of PD in “at high risk” patients with REM sleep behavior disorder basedThe early recognition of Parkinson’s disease (PD) and other synucleinopathies in prodromal stages has crucial implications ...

Clinical neurology

  • 2020 - 2024
  • 15 479 tis. Kč
  • 15 467 tis. Kč
  • MZ
Projekt

Effect of cognitive behavioral therapy for insomnia on emotion regulation (NW24J-04-00083)

Insomnia is the most common sleep disorder and the second most prevalent mental disorder. Research demonstrates common comorbidity of insomnia and other mental health difficulties related to the altered REM sle...

Neurosciences (including psychophysiology)

  • 2024 - 2027
  • 6 492 tis. Kč
  • 6 492 tis. Kč
  • MZ
Projekt

Narcolepsy – clinical picture, pathophysiology, ageing, comorbidities and physical activity regimen (NT13238)

and on REM sleep without atonia. We will analyze differences between N+C and N-CNarcolepsy is a neurological disease characterized especially by excessive daytime sleepiness. It presents with two forms – narcolepsy with ca...

FH - Neurologie, neurochirurgie, neurovědy

  • 2012 - 2015
  • 7 079 tis. Kč
  • 6 704 tis. Kč
  • MZ
Projekt

Synucleinopathy - gut microbiota, pathophysiology, and biomarkers of progression (NW25-04-00079)

is preceded by a prodromal period with isolated REM sleep behavior disorder (iRBD). OneSynucleinopathies - Parkinson's disease (PD), dementia with Lewy bodies (DLB) and multisystem atrophy are currently incurable ...

Neurosciences (including psychophysiology)

  • 2025 - 2028
  • 18 857 tis. Kč
  • 18 857 tis. Kč
  • MZ
Projekt

Diagnostic and progressive potential of speech dual-tasking in basal ganglia disorders evidence from Parkinson's disease and Huntington's disease (NW25-04-00052)

in up to 90% of patients with basal ganglia disorders such as Parkinson's disease (PD) and Huntington's disease (HD). Speech impairment can occur since the prodromal stages and becomes more severe as the disease p...

Clinical neurology

  • 2025 - 2028
  • 10 344 tis. Kč
  • 10 344 tis. Kč
  • MZ
Projekt

Disorders of sleep and wakefulness and melatonin - relation to neurological diseases. (IZ4181)

Correlation of actigraphic and hormonal studies of sleep and waking disorders. Melatonin and cortisol profiles in patients with narcolepsy and hypersomnia, and in sleep disorders due to CNS deterioration Treatment ...

FH - Neurologie, neurochirurgie, neurovědy

  • 1997 - 1999
  • 973 tis. Kč
  • 941 tis. Kč
  • MZ
Projekt

Video analysis of hypomimia in Parkinson's disease and other synucleinopathies (NU23J-04-00042)

, sufficiently sensitive to detect (i) hypomimia in patients with REM sleep behavior disorder-synucleinopathy (aSYN) is available that would allow early intervention to prevent the disease manifestation of aSYN

Neurosciences (including psychophysiology)

  • 2023 - 2026
  • 6 843 tis. Kč
  • 6 843 tis. Kč
  • MZ
Projekt

Disorders of gait, postural stability and cognition in Parkinson's disease presymptomatic detection and targeted rehabilitation (NU20-04-00327)

produces cognitive impairment from the onset of the disease. However, in the premotor stages of synucleinopathies, ie. in subjects with idiopathic REM sleep disorder (iRBDDisorders of gait and stability g...

Neurosciences (including psychophysiology)

  • 2020 - 2024
  • 13 016 tis. Kč
  • 12 950 tis. Kč
  • MZ
  • 1 - 10 z 4 157