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17 (0,088s) •

Projekt

Novel genomic and biotechlological approaches in molecular oncology a way to the early diagnostics and targeted therapy (2B06106)

The aim of this project is to collect samples of head and neck squamous carcinomas and to screen them for differences in gene expression. This will be achieved by microarray analysis, SAGE, and real-time PCR methods. Clinical and molecular data will ...

EB - Genetika a molekulární biologie

  • 2006 - 2011
    • •
  • 103 674 tis. Kč
    • •
  • 91 849 tis. Kč
    • •
  • MŠMT
Projekt

New target genes for childhood leukemia diagnosis and treatment focused on adaptor molecules of signaling pathways (2B06064)

The aim of this project is a generation of new diagnostic and terapeutic means for human cancer. New childhood leukemia-specific target genes will be selected based on meta-analysis of differentially expressed transcripts from available published exp...

FD - Onkologie a hematologie

  • 2006 - 2011
    • •
  • 29 140 tis. Kč
    • •
  • 25 820 tis. Kč
    • •
  • MŠMT
Projekt

Receptor tyrosin kinases and downstream signaling pathways as possible therapeutic targets in pediatric refractory solid tumors (NV16-34083A)

This project is aimed at a detailed analysis of activity of the RTK and the downstream signaling pathways in high-risk refractory pediatric solid tumors. Individual or paired samples of tumor tissue taken from the individual patients should be includ...

FG - Pediatrie

  • 2016 - 2019
    • •
  • 14 468 tis. Kč
    • •
  • 14 468 tis. Kč
    • •
  • MZ
Projekt

Function of Positive Transcription Elongation Factor b (P-TEFb) in cardiac hypertrophy (GA301/09/1832)

Cardiac hypertrophy and ensuing heart failure are among the most common causes of mortality worldwide. Among many clinical symptoms, cardiac hypertrophy is recognized by elevated growth of heart wall due to global increase in RNA and protein synthesi...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2009 - 2011
    • •
  • 3 186 tis. Kč
    • •
  • 3 186 tis. Kč
    • •
  • GA ČR
Projekt

Research and Development of Cochlear Implants and their Application in the Clinical Practise (OC 244.70.95)

EI - Biotechnologie a bionika

  • 1993 - 1995
    • •
  • 245 tis. Kč
    • •
  • 440 tis. Kč
    • •
  • MŠMT
Projekt

Research and development of design, measurement methodology and production technology of rolling elements with a logarithmic raceway profile (EI22_002/0000082)

Projekt je zaměřen na VaV konstrukce, metodiky měření a technologie výroby valivých elementů s logaritmickým profilem s cílem vyvinout optimální modifikaci oběžné dráhy, technologii výroby a měření a dosáhnout zvýšení kvalitativních parametr...

Mechanical engineering

  • 2022 - 2026
    • •
  • 34 631 tis. Kč
    • •
  • 0 tis. Kč
    • •
  • MPO
Projekt

Life-course de-standardization in the contemporary Czech Republic (GA403/09/0038)

We propose to employ qualitative and quantitative methodology to investigate the de-standardization of the life course in the Czech Republic. We propose to study both its behavioral and normative aspects. The quantitative part of the project would re...

AO - Sociologie, demografie

  • 2009 - 2011
    • •
  • 2 694 tis. Kč
    • •
  • 2 694 tis. Kč
    • •
  • GA ČR
Projekt

Identification of novel therapeutic and disease progression monitoring targets within surface, transcriptional and signaling programme of childhood T-cell acute lymphoblastic leukemia cells (NU23J-03-00026)

Acute leukemia is the most common pediatric malignancy. T-cell acute lymphoblastic leukemia (T-ALL) originates from malignantly transformed T-lymphoblasts. Despite the improvements in prognosis (up to 85% overall survival), a fraction of patients rel...

Oncology

  • 2023 - 2026
    • •
  • 6 667 tis. Kč
    • •
  • 6 667 tis. Kč
    • •
  • MZ
Projekt

Study of a radio-block control and safety system for secondary lines and light-duty railway traffic. (1F42C/026/130)

The objective of this Project is to define the principles for designing a safety and control system for secondary and tramway lines. The České dráhy[Czech Railways] network has a large number of regional and secondary lines without any safet...

JO - Pozemní dopravní systémy a zařízení

  • 2004 - 2006
    • •
  • 2 901 tis. Kč
    • •
  • 2 901 tis. Kč
    • •
  • MD
Projekt

Unique biosynthetic enzymes as the key to novel bioactive compounds (NV17-30091A)

Effective search for producers of novel, pharmaceutically attractive natural compounds requires application of new screening techniques using genomic data. Growing information on the genetics of biosynthesis of natural compounds and their structural ...

EE - Mikrobiologie, virologie

  • 2017 - 2020
    • •
  • 7 493 tis. Kč
    • •
  • 7 493 tis. Kč
    • •
  • MZ
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