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1 289 (0,091s) •

Projekt

New approaches in targeted metabolomic analysis of unstable metabolites with oxo group labeling with quaternary ammonium and stable isotopes (GA23-06600S)

hydroxylamine reagents with permanent positive charge and stable isotope labels, which have...

Analytical chemistry

  • 2023 - 2025
    • •
  • 7 756 tis. Kč
    • •
  • 7 756 tis. Kč
    • •
  • GA ČR
Projekt

Multidimensional chromatography - mass spectrometry quantitative workflows in detailed characterization of human plasma lipidome (GA21-20238S)

plasma using two complementary approaches based on 13C stable isotope labeling and chemical derivatization with labeled agents. Labeling approaches will be implemented......

Analytical chemistry

  • 2021 - 2023
    • •
  • 9 310 tis. Kč
    • •
  • 9 310 tis. Kč
    • •
  • GA ČR
Projekt

New approaches in body fluid metabolic profiling and their usage in clinical diagnostics. (NS9755)

Profiling of body fluid acidic metabolites via rapid phase-transfer derivatization of the species with chloroformates straightly in the fluid will be methodically innovated by two unique procedures: one is combining the compound derivati...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2008 - 2011
    • •
  • 3 739 tis. Kč
    • •
  • 2 752 tis. Kč
    • •
  • MZ
Projekt

Laser Induced Sila Derivatization of Fullerenes (ME 019)

CC - Organická chemie

  • 1996 - 1997
    • •
  • 760 tis. Kč
    • •
  • 382 tis. Kč
    • •
  • MŠMT
Projekt

New derivatizing reagants for analysis of chiral alcohols (GA203/98/0462)

The presented proposal deals with new ways of the optical purity determination of biologically active compounds of either synthetic or natural origin. For that purpose, new derivatizing agents were designed and are believed to give with chir...

CC - Organická chemie

  • 1998 - 2000
    • •
  • 814 tis. Kč
    • •
  • 423 tis. Kč
    • •
  • GA ČR
Projekt

Development of new methods for determination of vitamin D metabolites in biological material. (1A8634)

Developing and validation of method for determination of circulating endogenous vitamin D hydroxylated metabolites using immunochemical and chromatographic techniques with UV or fluorimetric detection of native or derivatized analytes. Deter...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2005 - 2007
    • •
  • 2 562 tis. Kč
    • •
  • 2 535 tis. Kč
    • •
  • MZ
Projekt

Comprehensive characterization of histone epigenetic marks (GA22-28190S)

derivatization of histone lysine residues. However, those analyses are challenging, mainly of histone peptides using novel derivatization agents, digestion using alternative......

Analytical chemistry

  • 2022 - 2024
    • •
  • 6 324 tis. Kč
    • •
  • 6 082 tis. Kč
    • •
  • GA ČR
Projekt

Monitoring steroids and phytosterols in the aquatic ecosystem (LH13045)

The main objective of the project is to develop analytical methods for analysis of selected steroid hormones and phytosterols by GC-MS and LC-MS based on new extraction and derivatization procedures for the target analytes. The best techniqu...

CB - Analytická chemie, separace

  • 2013 - 2015
    • •
  • 1 294 tis. Kč
    • •
  • 1 294 tis. Kč
    • •
  • MŠMT
Projekt

Detection of per- and polyfluoroalkyl substances by simple colorimetric assays (LUAUS26028)

the selection of the most suitable derivatization agents for selective detection...

Environmental sciences (social aspects to be 5.7)

  • 2026 - 2029
    • •
  • 7 986 tis. Kč
    • •
  • 7 986 tis. Kč
    • •
  • MŠMT
Projekt

Rapid analysis of biochemical markers in body fluids in the diagnosis of metabolic disorders. (NB4848)

Analysis of physiological fluid metabolites (carboxylic acid and their conjugates, peptides, biogenic amines) by capillary gas chromatography following a preceding derivatization with chloroformates in order to follow markers of metabolic di...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 1998 - 2000
    • •
  • 3 124 tis. Kč
    • •
  • 2 515 tis. Kč
    • •
  • MZ
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