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Projekt

The participation of microorganisms and other factors in the process of autoimmune uveitis (NV17-31248A)

uveitis, and model of the experimental autoimmune uveitis (EAU) in mice, including-threatening autoimmune uveitis. Special emphasis will be put on clarifying the influence to those from clinical ...

FF - ORL, oftalmologie, stomatologie

  • 2017 - 2020
    • •
  • 11 679 tis. Kč
    • •
  • 11 679 tis. Kč
    • •
  • MZ
Projekt

The Role of Microorganisms in the Process of Autoimmune Uveitis (NT14017)

(including commensal bacteria) in the process of autoimmune uveitis in human medicine and on the experimental model of autoimmune uveitis, using also the unique gnotobiotic model (germ cause in geneticall...

EE - Mikrobiologie, virologie

  • 2013 - 2015
    • •
  • 5 808 tis. Kč
    • •
  • 5 808 tis. Kč
    • •
  • MZ
Projekt

Study of probiotic supplementation effects in the treatment of non-infectious uveitis (NU23-05-00133)

was described in a model of experimentally induced autoimmune uveitis in mice. It is assumed with autoimmune uveitis, who will have parallel to their standard therapy a long-term autoimmune u...

Ophthalmology

  • 2023 - 2026
    • •
  • 14 022 tis. Kč
    • •
  • 14 022 tis. Kč
    • •
  • MZ
Projekt

Role of retinal neural activity in pathogenesis of autoimmune uveitis (GJ18-11795Y)

Autoimmune posterior uveitis is a CD4+ T cell-mediated inflammatory disease of the choroid and retina that results in blindness. Disruption of blood-retinal barrier (BRB) is considered as a critical early phenomenon towards disease ...

Neurosciences (including psychophysiology)

  • 2018 - 2022
    • •
  • 6 279 tis. Kč
    • •
  • 5 975 tis. Kč
    • •
  • GA ČR
Projekt

Uveitis,diagnosis,therapy and surgery (IZ3174)

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1995 - 1997
    • •
  • 305 tis. Kč
    • •
  • 276 tis. Kč
    • •
  • MZ
Projekt

Uveitis-pathogenesis,diagnosis and long-term therapy. (IZ1050)

9F - 9

  • 1992 - 1994
    • •
  • 0 tis. Kč
    • •
  • 0 tis. Kč
    • •
  • MZ
Projekt

Autoimmune diseases and nitric oxide - pharmacotherapeutic aspects (GA307/97/0069)

The project is aimed in elucidating the role of nitric oxide (no) in pathogenesis of autoimmune diseases. Both quantitative and qualitative aspects of NO production in various cells, tissues and organs will be analysed. Experimental...

FR - Farmakologie a lékárnická chemie

  • 1997 - 1999
    • •
  • 5 068 tis. Kč
    • •
  • 3 145 tis. Kč
    • •
  • GA ČR
Projekt

The role of CMTM4 in IL-17 receptor signaling (GJ20-24912Y)

and IL-17 dependent autoimmune disease models: imiquimod-induced psoriasis and experimental autoimmune encephalomyelitis. Finally, we will study what other signaling of IL-17 promotes a variety of autoimmune disor...

Cell biology

  • 2020 - 2022
    • •
  • 8 436 tis. Kč
    • •
  • 8 436 tis. Kč
    • •
  • GA ČR
Projekt

Gut microbiota and the role of food additives in the development of allergies and autoimmune diseases (GA15-09518S)

The incidence of allergies and autoimmune diseases is increasing worldwide. According to current knowledge the abnormal composition of gut microbiota characterized will be studied in detail in standard experimental models. The main ...

EC - Imunologie

  • 2015 - 2019
    • •
  • 5 688 tis. Kč
    • •
  • 5 688 tis. Kč
    • •
  • GA ČR
Projekt

Autoimmmune thyroiditis, infectious pathogenesis of Helicobacter and genetics (NR8115)

Monitoring of the influence of the members of Helicobacter family on the development of autoimmune mechanisms in autoimmune thyroiditis, polyglandular activation of autoimmunity and thyrogastric syndrome in the frame of APS...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2004 - 2006
    • •
  • 3 585 tis. Kč
    • •
  • 3 581 tis. Kč
    • •
  • MZ
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