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Projekt

Targeted damage of the DNA repair mechanisms as a tool for cancer therapy (NV15-31604A)

diverse unnatural nucleotide units (nucleoside analogs and/or phosphonate types...

EB - Genetika a molekulární biologie

  • 2015 - 2018
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  • 17 562 tis. Kč
    • •
  • 17 562 tis. Kč
    • •
  • MZ
Projekt

Analog mixing console (EI22_002/0000550)

The goal of the project is the development of a new analog mixing desk, which will primarily stand out with exceptional sound quality, high resolution, low distortion, yet compact dimensions and high energy efficiency......

Electrical and electronic engineering

  • 2023 - 2026
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  • 9 853 tis. Kč
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  • 0 tis. Kč
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  • MPO
Projekt

Research of new analog integrated circuits design principles for battery-powered implantable and wearable biomedical devices (GA15-21942S)

minimizing the power consumption and supply voltage of the circuits. However, analog of the analog circuits with scaling down their supply voltage, owing to the fact with research of new low-voltage low-power analog circui...

JA - Elektronika a optoelektronika, elektrotechnika

  • 2015 - 2017
    • •
  • 4 967 tis. Kč
    • •
  • 4 967 tis. Kč
    • •
  • GA ČR
Projekt

Methods of Signal Digitizing for Advanced Sensors (GA102/08/1116)

and development of digital to analog and analog to digital converters have to fulfil to analog and analog to digital converter realization is demand for power supply structures in recent design of digital and ...

JA - Elektronika a optoelektronika, elektrotechnika

  • 2008 - 2010
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  • 4 715 tis. Kč
    • •
  • 4 715 tis. Kč
    • •
  • GA ČR
Projekt

New full-length analogs of human insulin with modifications in positions B24-B26. (KJB400550702)

full-length analogs of human insulin with modifications in the positions B24-B26, Ala and Me-Ala. Resulting analogs will be tested for their binding affinity to the insulin receptor. The most interesting insulin analogs wi...

CE - Biochemie

  • 2007 - 2009
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  • 2 320 tis. Kč
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  • 2 320 tis. Kč
    • •
  • AV ČR
Projekt

Phosphonate-based 2'-5' oligoadenylate analogs a novel metabolically stable potential activators of RNase L. (IAA4055101)

diverse phosphonate 2',5'-oligoadenylate (2-5A) analogs as potential activators the solid-phase synthesis of 2-5A analogs, the spontaneous heavy metal-catalysed oligomerzation of activated phosphonate monomers in solution leading t...

CC - Organická chemie

  • 2001 - 2005
    • •
  • 15 202 tis. Kč
    • •
  • 4 405 tis. Kč
    • •
  • AV ČR
Projekt

Neuroprotective effects of novel analogs of anorexigenic prolactin-releasing peptide (PrRP) in mouse models of neurodegeneration and obesity (GA16-00918S)

anorexigenic peripherally administered and centrally acting analogs of prolactin-releasing. Implication of PrRP analogs on spatial memory will be also assessed. Besides, effects of PrRP analogs on induced neuronal damage i...

FH - Neurologie, neurochirurgie, neurovědy

  • 2016 - 2018
    • •
  • 8 583 tis. Kč
    • •
  • 7 815 tis. Kč
    • •
  • GA ČR
Projekt

Neuropeptide FF-2 receptor as a potential anti-obesity target Impact of new analogs of RF-amide peptides (GA21-03691S)

-2R, respectively. We have already demonstrated that lipidized PrRP analogs analogs with best affinity to and activation of signaling pathways in cell lines peptide analogs on individual receptors in NPFF-2R knockout (KO) a...

Physiology (including cytology)

  • 2021 - 2023
    • •
  • 11 297 tis. Kč
    • •
  • 10 676 tis. Kč
    • •
  • GA ČR
Projekt

Syntheses of the 4 - substituted nucleoside carba analogs with potentional antiviral effects (GA203/97/0375)

In continuation of the previous studies aimed at the syntheses of 4'-C-substituted deoxynucleosides with a potential antiviral activity, this research project concerns syntheses of novel 4'-substituted 2'-deoxynucleoside carba analogs. We pl...

CC - Organická chemie

  • 1997 - 1999
    • •
  • 920 tis. Kč
    • •
  • 322 tis. Kč
    • •
  • GA ČR
Projekt

Analog filter synthesis (GA102/02/1067)

This project is oriented to the optimum design of prospective analog subsystems suitable to cooperate with digital signal-processing systems in the form of analog Front-End and subsystems for analog signal pre- and post-pro...

JA - Elektronika a optoelektronika, elektrotechnika

  • 2002 - 2004
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  • 837 tis. Kč
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  • 837 tis. Kč
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  • GA ČR
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