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3 225 (0,144s)

Projekt

Whole genome sequencing in genome and transcriptome analyses of Treponema pathogens (GAP302/12/0574)

) genomic sequencing of treponemal strains and ii) sequencing analyses of transcriptomes and identification of T. pallidum promoters. At least 10 pathogenic treponemes will be sequenced to obtain high quality genom...

EE - Mikrobiologie, virologie

  • 2012 - 2016
  • 10 673 tis. Kč
  • 10 673 tis. Kč
  • GA ČR
Projekt

Genomics for the modern diagnostics and treatment of childhood leukaemias (NU20-07-00322)

the genetic and genomic classification, we will apply next-generation sequencing (mostly whole transcriptome and genome sequencing) to classify so far genetically non-defined subgroups of ALL. Moreover, we will te...

Paediatrics

  • 2020 - 2023
  • 17 048 tis. Kč
  • 17 048 tis. Kč
  • MZ
Projekt

Whole exome, low-coverage genome and transcriptome sequencing as tools for precision oncology in paediatric patients with high-risk and relapsed solid tumors (NU20-03-00240)

. The overall aim of this project is an utilization of whole exome sequencing, genome sequencing with low coverage and transcriptome sequencing as important tools can be identified by modern methods based ...

Oncology

  • 2020 - 2023
  • 17 455 tis. Kč
  • 17 455 tis. Kč
  • MZ
Projekt

Mesopolyploid events in the evolution of Brassicaceae (GA13-10159S)

-diploids. Whole-transcriptome sequence analysis will be employed to corroborate by comparative chromosome painting and transcriptome sequencing. We will reconstructWhole-genome duplication (WGD) ...

EB - Genetika a molekulární biologie

  • 2013 - 2017
  • 6 835 tis. Kč
  • 6 835 tis. Kč
  • GA ČR
Projekt

Genomics of Treponema comparative genome sequencing of pathogenic treponemes and transcriptome analysis of T. pallidum ssp. pallidum (GA310/07/0321)

of the genus Treponema using methods of comparative genomics including the whole genome fingerprinting method (WGF), comparative genome sequencing (CGS) approach and Chromatin Immunoprecipitation method (ChIP-chip). Genomes of five...

EB - Genetika a molekulární biologie

  • 2007 - 2011
  • 9 235 tis. Kč
  • 9 235 tis. Kč
  • GA ČR
Projekt

Transcriptome changes and genome integrity in human subjects acutely and chronically exposed to nanoparticles (GA22-08358S)

blood samples will be used for detail whole genome transcriptomic analysis (including mRNA and miRNA) by next generation sequencing and to investigate differences......

Toxicology

  • 2022 - 2024
  • 7 070 tis. Kč
  • 7 070 tis. Kč
  • GA ČR
Projekt

Whole transcriptome study of transgenic barley with altered cytokinin homeostasis (GA14-12355S)

to enhanced yield. Using next-generation sequencing, we will characterize transcriptomeThe breeding strategies face two central problems: higher yield and adaptation to adverse environmental conditions. The project is focused on

EB - Genetika a molekulární biologie

  • 2014 - 2016
  • 6 568 tis. Kč
  • 6 568 tis. Kč
  • GA ČR
Projekt

Activity of novel compounds against Burkholderia cenocepacia a study of genome and transcriptome in respect to bacterial evolution in the human host (NV15-28017A)

. The whole genome sequencing and RNA-seq will be utilized for comparative genomics of ca are to describe inhibitory effect of novel compounds on the transcriptomic level (molecules......

EE - Mikrobiologie, virologie

  • 2015 - 2018
  • 4 602 tis. Kč
  • 4 602 tis. Kč
  • MZ
Projekt

Long and short-term species response to aridification using the true Rose of Jericho as a model (GA24-10107S)

will perform whole genome and transcriptome sequencing to study long-term phylogeographical patterns and transcriptome sequencing to understand potential for adaptation within......

Plant sciences, botany

  • 2024 - 2026
  • 14 313 tis. Kč
  • 14 313 tis. Kč
  • GA ČR
Projekt

Integrative analysis of high-throughput genomics and multiparameter flow cytometry to improve diagnosis and monitoring of childhood acute leukemia (NV18-08-00385)

will allow for optimisation of MRD detection. Moreover, we will use whole genome data...

Medical laboratory technology (including laboratory samples analysis; diagnostic technologies) (Biomaterials to be 2.9 [physical characteristics of living material as related to medical implants, devices, sensors])

  • 2018 - 2021
  • 7 624 tis. Kč
  • 7 624 tis. Kč
  • MZ
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